CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045129
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger protein 426 
Protein Synonyms/Alias
  
Gene Name
 ZNF426 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
143HDCNQYGKDFLTLCEubiquitination[1]
157EKTSTGEKLSEFNQSubiquitination[1]
166SEFNQSEKIFSLTPNubiquitination[1, 2]
184QRTSTQEKSFECSHCubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 516 AA 
Protein Sequence
MDSVTFDDVA VDFTQEEWTL LDSTQRSLYS DVMLENYKNL ATVGGQIIKP SLISWLEQEE 60
SRTVQGGVLQ GWEMRLETQW SILQQDFLRG QTSIGIQLEG KHNGRELCDC EQCGEVFSEH 120
SCLKTHVRTQ STGNTHDCNQ YGKDFLTLCE KTSTGEKLSE FNQSEKIFSL TPNIVYQRTS 180
TQEKSFECSH CGKSFINESY LQAHMRTHNG EKLYEWRNYG PGFIDSTSLS VLIETLNAKK 240
PYKCKECGKG YRYPAYLSIH MRTHTGEKPY ECKECGKAFN YSNSFQIHGR THTGEKPYVC 300
KECGKAFTQY SGLSMHVRSH SGDKPYECKE CGKSFLTSSR LIQHIRTHTG EKPFVCVECG 360
KAFAVSSNLS GHLRTHTEEK ACECKICGKV FGYPSCLNNH MRTHSAQKPY TCKECGKAFN 420
YSTHLKIHMR IHTGEKPYEC KQCGKAFSHS SSFQIHERTH TGEKPYECKE CGKAFTCSSS 480
FRIHEKTHTE EKPYKCQQCG KAYSHPRSLR RHEQIH 516 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS