UniProt Accession

 NUDC_ECOLI; P32664; Q2M8T3; Q6BEX6 

Genbank Protein ID

 D12624; U00006; U00096; AP009048 

Genbank Nucleotide ID

 AAC43094.1; AAT48238.1; BAE77323.1 

Protein Name

 NADH pyrophosphatase 

Protein Synonyms/Alias

  

Gene Name

 nudC 

Gene Synonyms/Alias

 yjaD; b3996; JW5548 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
7	*MDRIIEKLDHGWWV	acetylation	[1]
20	WVVSHEQKLWLPKGE	acetylation	[1]
25	EQKLWLPKGELPYGE	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

  

Sequence Annotation

 DOMAIN 125 248 Nudix hydrolase.
 MOTIF 159 180 Nudix box.
 METAL 98 98 Zinc.
 METAL 101 101 Zinc.
 METAL 116 116 Zinc.
 METAL 119 119 Zinc.
 METAL 174 174 Divalent metal cation (By similarity).
 METAL 178 178 Divalent metal cation (By similarity).  

Keyword

 3D-structure; Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding; NAD; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 257 AA 

Protein Sequence

Gene Ontology

 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0030145; F:manganese ion binding; IDA:EcoCyc.
 GO:0000210; F:NAD+ diphosphatase activity; IEA:HAMAP.
 GO:0035529; F:NADH pyrophosphatase activity; IDA:EcoCyc.
 GO:0008270; F:zinc ion binding; IEA:HAMAP. 

Interpro

 IPR015375; NADH_PPase-like_N.
 IPR022925; NADH_pyroPase_NudC.
 IPR020084; NUDIX_hydrolase_CS.
 IPR000086; NUDIX_hydrolase_dom.
 IPR015797; NUDIX_hydrolase_dom-like.
 IPR015376; Znr_NADH_PPase. 

Pfam

 PF00293; NUDIX
 PF09296; NUDIX-like
 PF09297; zf-NADH-PPase 

SMART

  

PROSITE

 PS51462; NUDIX
 PS00893; NUDIX_BOX 

PRINTS