UniProt Accession

 D6REM0_HUMAN; D6REM0 

Genbank Protein ID

 AC097712; AC105394; AC107383; AC107392 

Genbank Nucleotide ID

  

Protein Name

 Gamma-aminobutyric acid receptor subunit beta-1 

Protein Synonyms/Alias

  

Gene Name

 GABRB1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
94	DTYFLNDKKSFVHGV	ubiquitination	[1, 2, 3]
95	TYFLNDKKSFVHGVT	ubiquitination	[2]
104	FVHGVTVKNRMIRLH	ubiquitination	[2]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 117 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0030425; C:dendrite; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005635; C:nuclear envelope; IEA:Compara.
 GO:0043235; C:receptor complex; IEA:Compara.
 GO:0005253; F:anion channel activity; IEA:Compara.
 GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
 GO:0004890; F:GABA-A receptor activity; IEA:Compara.
 GO:0021954; P:central nervous system neuron development; IEA:Compara.
 GO:0042698; P:ovulation cycle; IEA:Compara.
 GO:0032570; P:response to progesterone stimulus; IEA:Compara.
 GO:0009636; P:response to toxic substance; IEA:Compara. 

Interpro

 IPR006202; Neur_chan_lig-bd.
 IPR006201; Neur_channel. 

Pfam

 PF02931; Neur_chan_LBD 

SMART

  

PROSITE

  

PRINTS