CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031264
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ52761, highly similar to Actin, aortic smooth muscle 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
7*MVGMGQKDSYVGDEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 332 AA 
Protein Sequence
MVGMGQKDSY VGDEAQSKRG ILTLKYPIEH GIITNWDDME KIWHHSFYNE LRVAPEEHPT 60
LLTEAPLNPK ANREKMTQIM FETFNVPAMY VAIQAVLSLY ASGRTTGIVL DSGDGVTHNV 120
PIYEGYALPH AIMRLDLAGR DLTDYLMKIL TERGYSFVTT AEREIVRDIK EKLCYVALDF 180
ENEMATAASS SSLEKSYELP DGQVITIGNE RFRCPETLFQ PSFIGMESAG IHETTYNSIM 240
KCDIDIRKDL YANNVLSGGT TMYPGIADRM QKEITALAPS TMKIKIIAPP ERKYSVWIGG 300
SILASLSTFQ QMWISKQEYD EAGPSIVHRK CF 332 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; IEA:Compara.
 GO:0030485; C:smooth muscle contractile fiber; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008217; P:regulation of blood pressure; IEA:Compara.
 GO:0014829; P:vascular smooth muscle contraction; IEA:Compara. 
Interpro
 IPR004000; Actin-related.
 IPR020902; Actin/actin-like_CS.
 IPR004001; Actin_CS. 
Pfam
 PF00022; Actin 
SMART
 SM00268; ACTIN 
PROSITE
 PS00406; ACTINS_1
 PS00432; ACTINS_2
 PS01132; ACTINS_ACT_LIKE 
PRINTS
 PR00190; ACTIN.