| Tag | Content |
|---|
| CPLM ID | CPLM-011008 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | NET1-associated nuclear protein 1 |
Protein Synonyms/Alias | U three protein 17; t-17; U3 protein 17 required for transcription; U3 small nucleolar RNA-associated protein 17; U3 snoRNA-associated protein 17 |
Gene Name | NAN1 |
Gene Synonyms/Alias | UTP17; YPL126W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 483 | GVNNSMGKVRFELNL | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs). |
Sequence Annotation | REPEAT 295 334 WD 1.
REPEAT 490 542 WD 2.
REPEAT 552 595 WD 3.
REPEAT 605 645 WD 4. |
Keyword | Complete proteome; Nucleus; Reference proteome; Repeat; Ribonucleoprotein; Ribosome biogenesis; rRNA processing; Transcription; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 896 AA |
Protein Sequence | MTQSLGIEQY KLSVVSGGKP ALNNLSSVTG NKNIARLSQD QRNYIIPFNN QIKVYSVETR 60
QCVKTLKFAN NSLLSGIFLQ EEENNESIVK ILLGDITVPQ QEDAHLITVF TNNGHVIVLN 120
YKGKLVESPK HFKISLADEK LANVFHSEGN YRILTTFKDP SQKAHNSLQS YRLYALTFDD 180
AKKQFEVAHQ AEWHNVILSN ISSNGKLLAH MCKDVSTKDH EHKSISVVSL FDDSVNLSFP 240
LGSILSSQTQ SLSYNTRYVS SMAIDNMGQQ LAVGFASGVI SIVSLADLQI RLLKWHIDSV 300
LSLSFSHDGS YLLSGGWEKV MSLWQLETNS QQFLPRLNGI IIDCQVLGPQ GNYYSLILQM 360
TENNSNSDYQ FLLLNASDLT SKLSINGPLP VFNSTIKHIQ QPISAMNTKN SNSITSLNHS 420
KKKQSRKLIK SRRQDFTTNV EINPINKNLY FPHISAVQIF DFYKNEQVNY QYLTSGVNNS 480
MGKVRFELNL QDPIITDLKF TKDGQWMITY EIEYPPNDLL SSKDLTHILK FWTKNDNETN 540
WNLKTKVINP HGISVPITKI LPSPRSVNNS QGCLTADNNG GLKFWSFDSH ESNWCLKKIS 600
LPNFNHFSNS VSLAWSQDGS LIFHGFDDKL QILDFDTFKK FESLENTKTV SEFTLDSEIQ 660
TVKLINDTNL IVATRTTLNA INLLRGQVIN SFDLYPFVNG VYKNGHMDRL ITCDERTGNI 720
ALVINQQLTD LDGVPTINYK SRIIIFDSDL STKLGNFTHH EYISWIGWNY DTDFIFLDIE 780
STLGVVGTTV NTQLSDEVNN EGILDGLVSN TITTSASNSD IFAEQLHKLS SRGKKSDTRD 840
KNTNDNDEDE EDIALEFING EKKDKLVNMN SFTSMFDNIQ NVQMDTFFDR VMKVLT 896 |
Gene Ontology | GO:0033553; C:rDNA heterochromatin; IDA:SGD. GO:0032040; C:small-subunit processome; IDA:SGD. GO:0034455; C:t-UTP complex; IDA:SGD. GO:0030515; F:snoRNA binding; IPI:SGD. GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:SGD. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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Pfam | |
SMART | |
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