CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025802
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Proteasome 26S non-ATPase subunit 2 variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
36TDEKPSGKERRDAGDubiquitination[1]
71LVERLGEKDTSLYRPubiquitination[1]
99TSMTSVPKPLKFLRPubiquitination[1]
102TSVPKPLKFLRPHYGubiquitination[1]
297CKDVVVQKQMAFMLGubiquitination[1]
355KVPDDIYKTHLENNRubiquitination[1]
402LLTDDGNKWLYKNKDubiquitination[1]
446YSSEDYIKSGALLACubiquitination[1]
759QLAQYHAKDPNNLFMubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Proteasome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 913 AA 
Protein Sequence
AVAAEMEEGG RDKAPVQPQQ SPAAAPGGTD EKPSGKERRD AGDKDKEQEL SEEDKQLQDE 60
LEMLVERLGE KDTSLYRPAL EELRRQIRSS TTSMTSVPKP LKFLRPHYGK LKEIYENMAP 120
GENKRFAADI ISVLAMTMSG ERECLKYRLV GSQEELASWG HEYVRHLAGE VAKEWQELDD 180
AEKVQREPLL TLVKEIVPYN MAHNAEHEAC DLLMEIEQVD MLEKDIDENA YAKVCLYLTS 240
CVNYVPEPEN SALLCCALGV FRKFSRFPEA LRLALMLNDM ELVEDIFTSC KDVVVQKQMA 300
FMLGRHGVFL ELSEDVEEYE DLTEIMSNVQ LNSNFLALAR ELDIMEPKVP DDIYKTHLEN 360
NRFGGSGSQV DSARMNLASS FVNGFVNAAF GQDKLLTDDG NKWLYKNKDH GMLSAAASLG 420
MILLWDVDGG LTQIDKYLYS SEDYIKSGAL LACGIVNSGV RNECDPALAL LSDYVLHNSN 480
TMRLGSIFGL GLAYAGSNRE DVLTLLLPVM GDSKSSMEVA GVTALACGMI AVGSCNGDVT 540
STILQTIMEK SETELKDTYA RWLPLGLGLN HLGKGEAIEA ILAALEVVSE PFRSFANTLV 600
DVCAYAGSGN VLKVQQLLHI CSEHFDSKEK EEDKDKKEKK DKDKKEAPAD MGAHQGVAVL 660
GIALIAMGEE IGAEMALRTF GHLLRYGEPT LRRAVPLALA LISVSNPRLN ILDTLSKFSH 720
DADPEVSYNS IFAMGMVGSG TNNARLAAML RQLAQYHAKD PNNLFMVRLA QGLTHLGKGT 780
LTLCPYHSDR QLMSQVAVAG LLTVLVSFLD VRNIILGKSH YVLYGLVAAM QPRMLVTFDE 840
ELRPLPVSVR VGQAVDVVGQ AGKPKTITGF QTHTTPVLLA HGERAELATE EFLPVTPILE 900
GFVILRKNPN YDL 913 
Gene Ontology
 GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
 GO:0030234; F:enzyme regulator activity; IEA:InterPro.
 GO:0050790; P:regulation of catalytic activity; IEA:GOC.
 GO:0042176; P:regulation of protein catabolic process; IEA:InterPro. 
Interpro
 IPR016643; 26S_Psome_Rpn1.
 IPR002015; APC_proteasome.
 IPR016024; ARM-type_fold. 
Pfam
 PF01851; PC_rep 
SMART
  
PROSITE
  
PRINTS