| Tag | Content |
|---|
| CPLM ID | CPLM-025023 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Histone H2B |
Protein Synonyms/Alias | |
Gene Name | Tb10.406.0330, Tb10.406.0350, Tb10.406.0360, Tb10.406.0370,Tb10.406.0380, Tb10.406.0400, Tb10.406.0410, Tb10.406.0420,Tb10.406.0430, Tb10.406.0440, Tb10.406.0450, Tb10.406.0460 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) |
NCBI Taxa ID | 999953 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 5 | ***MATPKSTPAKTR | acetylation | [1] | | 13 | STPAKTRKEAKKTRR | acetylation | [1] | | 17 | KTRKEAKKTRRQRKR | acetylation | [1] |
|
Reference | [1] Histone modifications in Trypanosoma brucei. Mandava V, Fernandez JP, Deng H, Janzen CJ, Hake SB, Cross GA. Mol Biochem Parasitol. 2007 Nov;156(1):41-50. [ PMID: 17714803] |
Functional Description | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). |
Sequence Annotation | |
Keyword | Chromosome; Complete proteome; DNA-binding; Isopeptide bond; Nucleosome core; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 112 AA |
Protein Sequence | MATPKSTPAK TRKEAKKTRR QRKRTWNVYV SRSLRSINSQ MSMTSRTMKI VNSFVNDLFE 60
RIAAEAATIV RVNRKRTLGA RELQTAVRLV LPADLAKHAM AEGTKAVSHA SS 112 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |