UniProt Accession

 NIPS2_HUMAN; O75323; C9IYJ3; O43801; Q53X96 

Genbank Protein ID

 AF029786; AJ001259; BT007112; AK097049; CR407612; AC092579; CH471140; CH471140; BC000732; BC001837; BC030821 

Genbank Nucleotide ID

 AAC29002.1; CAA04633.1; AAP35776.1; CAG28540.1; EAX07966.1; EAX07967.1; AAH00732.1; AAH01837.1; AAH30821.1 

Protein Name

 Protein NipSnap homolog 2 

Protein Synonyms/Alias

 NipSnap2; Glioblastoma-amplified sequence 

Gene Name

 GBAS 

Gene Synonyms/Alias

 NIPSNAP2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
47	SREDSWLKSLFVRKV	ubiquitination	[1, 2]
67	AHSNLLAKKETSNLY	ubiquitination	[1, 2]
148	MNKLRENKEFLEFRK	acetylation	[3]
281	SRIMIPLKTSPLQ**	ubiquitination	[4]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 286 AA 

Protein Sequence

Gene Ontology

 GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
 GO:0005739; C:mitochondrion; ISS:UniProtKB.
 GO:0006754; P:ATP biosynthetic process; IMP:BHF-UCL.
 GO:2000984; P:negative regulation of ATP citrate synthase activity; IMP:BHF-UCL.
 GO:0006119; P:oxidative phosphorylation; IMP:BHF-UCL. 

Interpro

 IPR011008; Dimeric_a/b-barrel.
 IPR012577; NIPSNAP. 

Pfam

 PF07978; NIPSNAP 

SMART

  

PROSITE

  

PRINTS