CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000776
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sjoegren syndrome nuclear autoantigen 1 
Protein Synonyms/Alias
 Nuclear autoantigen of 14 kDa 
Gene Name
 SSNA1 
Gene Synonyms/Alias
 NA14 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
97QTLLSVLKREAGNLTubiquitination[1, 2, 3, 4, 5, 6]
105REAGNLTKATAPDQKubiquitination[6]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [6] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
 MOD_RES 2 2 N-acetylthreonine.  
Keyword
 Acetylation; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Nucleus; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 119 AA 
Protein Sequence
MTQQGAALQN YNNELVKCIE ELCQKREELC RQIQEEEDEK QRLQNEVRQL TEKLARVNEN 60
LARKIASRNE FDRTIAETEA AYLKILESSQ TLLSVLKREA GNLTKATAPD QKSSGGRDS 119 
Gene Ontology
 GO:0005813; C:centrosome; IDA:UniProtKB.
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005634; C:nucleus; TAS:ProtInc.
 GO:0060830; P:ciliary receptor clustering involved in smoothened signaling pathway; IEA:Compara.
 GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
 GO:0042073; P:intraflagellar transport; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS