CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034069
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tripartite motif-containing protein 46 
Protein Synonyms/Alias
  
Gene Name
 Trim46 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
527RERLAISKDQRAVRSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 736 AA 
Protein Sequence
MKNMEKELLC PVCQEMYKQP LVLPCTHNVC QACAREVLGQ QGYIGHGGDP SSEPTSPAST 60
PSTRSPRLSR RTLPKPDRLD RLLKSGFGTY PGRKRGALHP QTILFPCPAC QGDVELGERG 120
LSGLFRNLTL ERVVERYRQS VSVGGAILCQ LCKPPPLEAT KGCTECRATF CNECFKLFHP 180
WGTQKAQHEP TLPTLSFRPK GLMCPDHKEE VTHYCKTCQR LVCQLCRVRR THSGHKITPV 240
LSAYQALKDK LTKSLAYILG NQDTVQTQIC ELEETIRHTE VSGQQAKEEV SQLVRGLGAV 300
LEEKRASLLQ AIEECQQERL SRLSAQIHEH QSLLDGSGLV GYAQEVLKET DQPCFVQAAK 360
QLHNRIARAT EALQTFRPAA SSSFRHCQLD VGREMKLLTE LSFLRVPEAP VIDTQRTFAY 420
DQIFLCWRLP PHSPPAWHYT VEFRRTDVPA QPGPTRWQRR EEVRGTSALL ENPDTGSVYV 480
LRVRGCNKAG YGEYSEDVHL HTPPAPVLHF FLDGRWGASR ERLAISKDQR AVRSIPGLPL 540
LLAAERLLTG CHLSVDVVLG DVAVTQGRSY WACAVDPASY LVKVGVGLES KLQESFQGAP 600
DVISPRYDPD SGHDSGAEDA AVEALPPFAF LTIGMGKILL GSGASSNAGL TGRDGPTASC 660
TVPLPPRLGI CLDYERGRVS FLDAVSFRGL LECPLDCSGP VCPAFCFIGG GAVQLQEPVG 720
TKPERKVTIG GFAKLD 736 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001870; B30.2/SPRY.
 IPR008985; ConA-like_lec_gl_sf.
 IPR017903; COS_domain.
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold.
 IPR000315; Znf_B-box.
 IPR018957; Znf_C3HC4_RING-type.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF00643; zf-B_box
 PF00097; zf-C3HC4 
SMART
 SM00336; BBOX
 SM00060; FN3
 SM00184; RING 
PROSITE
 PS50188; B302_SPRY
 PS51262; COS
 PS50853; FN3
 PS50119; ZF_BBOX
 PS00518; ZF_RING_1 
PRINTS