CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025755
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Signal recognition particle receptor beta subunit 
Protein Synonyms/Alias
 Signal recognition particle receptor, B subunit, isoform CRA_b 
Gene Name
 SRPRB 
Gene Synonyms/Alias
 hCG_2023561 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
191IAMAKSAKLIQQQLEubiquitination[1, 2]
199LIQQQLEKELNTLRVubiquitination[2]
230AQLGKKGKEFEFSQLubiquitination[2]
265ADIQDLEKWLAKIA*ubiquitination[2]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 GTP-binding; Nucleotide-binding; Receptor. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 271 AA 
Protein Sequence
MASADSRRVA DGGGAGGTFQ PYLDTLRQEL QQTDPTLLSV VVAVLAVLLT LVFWKLIRSR 60
RSSQRAVLLV GLCDSGKTLL FVRLLTGLYR DTQTSITDSC AVYRVNNNRG NSLTLIDLPG 120
HESLRLQFLE RFKSSARAIV FVVDSAAFQR EVKDVAEFLY QVLIDSMGLK NTPSFLIACN 180
KQDIAMAKSA KLIQQQLEKE LNTLRVTRSA APSTLDSSST APAQLGKKGK EFEFSQLPLK 240
VEFLECSAKG GRGDVGSADI QDLEKWLAKI A 271 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR024156; Small_GTPase_ARF.
 IPR019009; SRP_receptor_beta_su. 
Pfam
 PF09439; SRPRB 
SMART
  
PROSITE
 PS51417; ARF 
PRINTS