UniProt Accession

 RASF3_HUMAN; Q86WH2; Q86WH1 

Genbank Protein ID

 AY217662; AY217663; BC100951; BC100949 

Genbank Nucleotide ID

 AAO61687.1; AAO61688.1; AAI00952.1; AAI00950.1 

Protein Name

 Ras association domain-containing protein 3 

Protein Synonyms/Alias

  

Gene Name

 RASSF3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
145	PAKFALYKRCHREDQ	ubiquitination	[1]
207	NFLRILDKEEDEQLQ	ubiquitination	[2]
217	DEQLQNLKRRYTAYR	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

 DOMAIN 79 186 Ras-associating.
 DOMAIN 187 234 SARAH.
 MOD_RES 2 2 N-acetylserine.  

Keyword

 Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 238 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0007165; P:signal transduction; IEA:InterPro. 

Interpro

 IPR000159; Ras-assoc.
 IPR011524; SARAH_dom. 

Pfam

 PF00788; RA 

SMART

 SM00314; RA 

PROSITE

 PS50200; RA
 PS50951; SARAH 

PRINTS