CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002264
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription factor Adf-1 
Protein Synonyms/Alias
 ADH distal factor 1 
Gene Name
 Adf1 
Gene Synonyms/Alias
 CG15845 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
180TAVGKDQKPYFYEPPacetylation[1]
189YFYEPPLKRERSEEEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 May play an important role not only in the regulation of Adh expression but also in the transcription of other genes. 
Sequence Annotation
 DOMAIN 217 256 BESS.
 DNA_BIND 24 104 MADF.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 262 AA 
Protein Sequence
MHTLTAAIEM DKLDANLEQQ FDLNLIEAVK LNPVIYDRSH YNYKHFVRKA QTWKQIAETL 60
GVPEQKCTKR WKSLRDKFAR EMKLCQESRW RYFKQMQFLV DSIRQYRESL LGKCANGSQS 120
ANQVADPSQQ QQAQQQTVVD IFAQPFNGSA TTSAQALTHP HEITVTSDAQ LATAVGKDQK 180
PYFYEPPLKR ERSEEEHSDN MLNTIKIFQN NVSQAVSAED QSFGMVVTDM LNTLGVRQKA 240
EAKVHIIKYL TDMQLLAQHN KY 262 
Gene Ontology
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.
 GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.
 GO:0008345; P:larval locomotory behavior; NAS:FlyBase.
 GO:0040011; P:locomotion; IMP:FlyBase.
 GO:0007616; P:long-term memory; TAS:FlyBase.
 GO:0008355; P:olfactory learning; NAS:FlyBase.
 GO:0007416; P:synapse assembly; IMP:FlyBase. 
Interpro
 IPR004210; BESS_motif.
 IPR006578; MADF-dom. 
Pfam
 PF10545; MADF_DNA_bdg 
SMART
 SM00595; MADF 
PROSITE
 PS51031; BESS
 PS51029; MADF 
PRINTS