CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006043
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Solute carrier family 2, facilitated glucose transporter member 3 
Protein Synonyms/Alias
 Glucose transporter type 3, brain; GLUT-3 
Gene Name
 Slc2a3 
Gene Synonyms/Alias
 Glut-3; Glut3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
243VQEIQEMKDESVRMSubiquitination[1]
253SVRMSQEKQVTVLELubiquitination[1]
473EGQAHSGKGPAGVELubiquitination[1]
487LNSMQPVKETPGNA*ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Facilitative glucose transporter. Probably a neuronal glucose transporter. 
Sequence Annotation
 REGION 277 279 Defines substrate specificity (By
 CARBOHYD 43 43 N-linked (GlcNAc...).  
Keyword
 Complete proteome; Direct protein sequencing; Glycoprotein; Membrane; Reference proteome; Sugar transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 493 AA 
Protein Sequence
MGTTKVTPSL VFAVTVATIG SFQFGYNTGV INAPETILKD FLNYTLEERL EDLPSEGLLT 60
ALWSLCVAIF SVGGMIGSFS VGLFVNRFGR RNSMLLVNLL AIIAGCLMGF AKIAESVEML 120
ILGRLLIGIF CGLCTGFVPM YIGEVSPTAL RGAFGTLNQL GIVVGILVAQ IFGLDFILGS 180
EELWPGLLGL TIIPAILQSA ALPFCPESPR FLLINKKEED QATEILQRLW GTSDVVQEIQ 240
EMKDESVRMS QEKQVTVLEL FRSPNYVQPL LISIVLQLSQ QLSGINAVFY YSTGIFKDAG 300
VQEPIYATIG AGVVNTIFTV VSLFLVERAG RRTLHMIGLG GMAVCSVFMT ISLLLKDDYE 360
AMSFVCIVAI LIYVAFFEIG PGPIPWFIVA ELFSQGPRPA AIAVAGCCNW TSNFLVGMLF 420
PSAAAYLGAY VFIIFAAFLI FFLIFTFFKV PETKGRTFED IARAFEGQAH SGKGPAGVEL 480
NSMQPVKETP GNA 493 
Gene Ontology
 GO:0002080; C:acrosomal membrane; IDA:MGI.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IDA:UniProtKB.
 GO:0055056; F:D-glucose transmembrane transporter activity; IDA:UniProtKB.
 GO:0033300; F:dehydroascorbic acid transporter activity; IDA:UniProtKB. 
Interpro
 IPR002945; Glc_transpt_3.
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR003663; Sugar/inositol_transpt.
 IPR005829; Sugar_transporter_CS. 
Pfam
 PF00083; Sugar_tr 
SMART
  
PROSITE
 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1
 PS00217; SUGAR_TRANSPORT_2 
PRINTS
 PR01192; GLUCTRSPORT3.
 PR00171; SUGRTRNSPORT.