CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016739
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 WD repeat-containing protein 26 
Protein Synonyms/Alias
  
Gene Name
 Wdr26 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
192LGIIVRMKFLLLQQKubiquitination[1]
349KFSNDGTKLATGSKDubiquitination[1]
439VAWNPDGKRFVTGGQubiquitination[1]
516IMSFTISKNGRLALLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May be involved in MAPK pathways (By similarity). 
Sequence Annotation
 DOMAIN 103 135 LisH.
 DOMAIN 136 211 CTLH.
 REPEAT 333 372 WD 1.
 REPEAT 379 418 WD 2.
 REPEAT 424 464 WD 3.
 REPEAT 504 543 WD 4.
 REPEAT 546 588 WD 5.
 REPEAT 591 631 WD 6.
 MOD_RES 101 101 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 641 AA 
Protein Sequence
MQANGAGGGG GGGGGGQGQT PELACLSAQN GESSPSATSA GDLAHANGLL PAAPSAAGNN 60
SNSLSVNNGV PGGAAAASAT AAAAQATPEL GSSLKKKKRL SQSDEDVIRL IGQHLNGLGL 120
NQTVDLLMQE SGCRLEHPSA TKFRNHVMEG DWDKAENDLN ELKPLVHSPH AIVVRGALEI 180
SQTLLGIIVR MKFLLLQQKY LEYLEDGKVL EALQVLRCEL TPLKYNTERI HVLSGYLMCS 240
HAEDLRAKAE WEGKGTASRS KLLDKLQTYL PPSVMLPPRR LQTLLRQAVE LQRDRCLYHN 300
TKLDNNLDSV SLLIDHVCSR RQFPCYTQQI LTEHCNEVWF CKFSNDGTKL ATGSKDTTVI 360
IWQVDPDTHL LKLLKTLEGH AYGVSYIAWS PDDSYLVACG PDDCSELWLW NVQTGELRTK 420
MSQSHEDSLT SVAWNPDGKR FVTGGQRGQF YQCDLDGNLL DSWEGVRVQC LWCLSDGKTV 480
LASDTHQRVR GYNFEDLTDR NIVQEDHPIM SFTISKNGRL ALLNVATQGV HLWDLQDRVL 540
VRKYQGVTQG FYTIHSCFGG HNEDFIASGS EDHKVYIWHK RSELPIAELT GHTRTVNCVS 600
WNPQIPSMMA SASDDGTVRI WGPAPFIDHQ NIEEECSSMD S 641 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:Compara. 
Interpro
 IPR006595; CTLH_C.
 IPR006594; LisH_dimerisation.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00668; CTLH
 SM00667; LisH
 SM00320; WD40 
PROSITE
 PS50897; CTLH
 PS50896; LISH
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS