CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044714
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 GTPase Era, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 ERAL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
123LGAPNAGKSTLSNQLubiquitination[1, 2]
173PGIISPGKQKRHHLEubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 284 AA 
Protein Sequence
XSWRGARLVQ SVLRVWQVGP HVARERVIPF SSLLGFQRRC VSCVAGSAFS GPRLASASRS 60
NGQGSALDHF LGFSQPDSSV TPCVPAVSMN RDEQDVLLVH HPDMPENSRV LRVVLLGAPN 120
AGKSTLSNQL LGRKVFPVSR KVHTTRCQAL GVITEKETQV ILLDTPGIIS PGKQKRHHLE 180
LSLLEDPWKS MESADLVVVL VDVSDKWTRN QLSPQLLRCL TKYSQIPSVL VMNKQYLLTQ 240
AQPGPWEYHS AVLTSQTPEE ICANIIREKL LEHLPQEVPY NVQQ 284 
Gene Ontology
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003723; F:RNA binding; IEA:InterPro. 
Interpro
 IPR006073; GTP_binding_domain.
 IPR015946; KH_dom-like_a/b.
 IPR009019; KH_prok-type.
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom. 
Pfam
 PF01926; MMR_HSR1 
SMART
  
PROSITE
  
PRINTS
 PR00326; GTP1OBG.