CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004086
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Enterochelin esterase 
Protein Synonyms/Alias
 Ferric enterobactin esterase 
Gene Name
 fes 
Gene Synonyms/Alias
 b0585; JW0576 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
298QEGVLLEKLKAGEVSacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use. 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Ion transport; Iron; Iron transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 374 AA 
Protein Sequence
MFEVTFWWRD PQGSEEYSTI KRVWVYITGV TDHHQNSQPQ SMQRIAGTNV WQWTTQLNAN 60
WRGSYCFIPT ERDDIFSVPS PDRLELREGW RKLLPQAIAD PLNLQSWKGG RGHAVSALEM 120
PQAPLQPGWD CPQAPEIPAK EIIWKSERLK KSRRVWIFTT GDATAEERPL AVLLDGEFWA 180
QSMPVWPVLT SLTHRQQLPP AVYVLIDAID TTHRAHELPC NADFWLAVQQ ELLPLVKAIA 240
PFSDRADRTV VAGQSFGGLS ALYAGLHWPE RFGCVLSQSG SYWWPHRGGQ QEGVLLEKLK 300
AGEVSAEGLR IVLEAGIREP MIMRANQALY AQLHPIKESI FWRQVDGGHD ALCWRGGLMQ 360
GLIDLWQPLF HDRS 374 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0008849; F:enterochelin esterase activity; IDA:EcoCyc.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0046214; P:enterobactin catabolic process; IMP:EcoCyc.
 GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
 GO:0006826; P:iron ion transport; IEA:InterPro. 
Interpro
 IPR021764; Enterochelin_esterase_N.
 IPR000801; Esterase_put.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set. 
Pfam
 PF11806; DUF3327
 PF00756; Esterase 
SMART
  
PROSITE
  
PRINTS