| Tag | Content |
|---|
| CPLM ID | CPLM-004099 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Serine/threonine protein kinase KIN1 |
Protein Synonyms/Alias | |
Gene Name | KIN1 |
Gene Synonyms/Alias | YDR122W; YD9727.17 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 536 | SEIPESVKQRDVEVN | ubiquitination | [1] | | 666 | NSNNSINKPVQKTHS | ubiquitination | [1] | | 708 | NDSRGGNKGDFPALP | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Serine/threonine protein kinase involved in the regulation of exocytosis. Induces phosphorylation of SEC9 and its release from the plasma membrane to the cytosol. |
Sequence Annotation | DOMAIN 120 398 Protein kinase.
DOMAIN 1015 1064 KA1.
NP_BIND 126 134 ATP (By similarity).
ACT_SITE 269 269 Proton acceptor (By similarity).
BINDING 149 149 ATP (By similarity).
MOD_RES 534 534 Phosphoserine.
MOD_RES 593 593 Phosphoserine.
MOD_RES 646 646 Phosphoserine.
MOD_RES 764 764 Phosphoserine.
MOD_RES 986 986 Phosphoserine. |
Keyword | ATP-binding; Cell membrane; Complete proteome; Cytoplasm; Exocytosis; Kinase; Membrane; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1064 AA |
Protein Sequence | MDDYHVNTAF SMGRGNQQDD GNSESNSMHT QPSTMAPATL RMMGKSPQQQ QQQNTPLMPP 60
ADIKYANNGN SHQAEQKERQ VELEGKSREN APKPNTTSQS RVSSSQGMPK QFHRKSLGDW 120
EFVETVGAGS MGKVKLAKHR YTNEVCAVKI VNRATKAFLH KEQMLPPPKN EQDVLERQKK 180
LEKEISRDKR TIREASLGQI LYHPHICRLF EMCTLSNHFY MLFEYVSGGQ LLDYIIQHGS 240
IREHQARKFA RGIASALIYL HANNIVHRDL KIENIMISDS SEIKIIDFGL SNIYDSRKQL 300
HTFCGSLYFA APELLKANPY TGPEVDVWSF GVVLFVLVCG KVPFDDENSS VLHEKIKQGK 360
VEYPQHLSIE VISLLSKMLV VDPKRRATLK QVVEHHWMVR GFNGPPPSYL PKRVPLTIEM 420
LDINVLKEMY RLEFIDDVEE TRSVLVSIIT DPTYVLLSRQ YWTLAAKMNA ESSDNGNAPN 480
ITESFEDPTR AYHPMISIYY LTSEMLDRKH AKIRNQQQRQ SHENIEKLSE IPESVKQRDV 540
EVNTTAMKSE PEATLATKDT SVPFTPKNSD GTEPPLHVLI PPRLAMPEQA HTSPTSRKSS 600
DNQRREMEYA LSPTPQGNDY QQFRVPSTTG DPSEKAKFGN IFRKLSQRRK KTIEQTSVNS 660
NNSINKPVQK THSRAVSDFV PGFAKPSYDS NYTMNEPVKT NDSRGGNKGD FPALPADAEN 720
MVEKQREKQI EEDIMKLHDI NKQNNEVAKG SGREAYAAQK FEGSDDDENH PLPPLNVAKG 780
RKLHPSARAK SVGHARRESL KYMRPPMPSS AYPQQELIDT GFLESSDDNK SDSLGNVTSQ 840
TNDSVSVHSV NAHINSPSVE KELTDEEILQ EASRAPAGSM PSIDFPRSLF LKGFFSVQTT 900
SSKPLPIVRY KIMFVLRKMN IEFKEVKGGF VCMQRFSSNN VAAKREGTPR SIMPLSHHES 960
IRRQGSNKYS PSSPLTTNSI HQRKTSITET YGDDKHSGTS LENIHQQGDG SEGMTTTEKE 1020
PIKFEIHIVK VRIVGLAGVH FKKISGNTWL YKELASSILK ELKL 1064 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0009898; C:internal side of plasma membrane; IDA:SGD. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. GO:0006887; P:exocytosis; IGI:SGD. GO:0046777; P:protein autophosphorylation; IDA:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |