CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044001
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dual-specificity protein phosphatase 7 
Protein Synonyms/Alias
  
Gene Name
 DUSP7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
201TNLDVLGKYGIKYILubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 275 AA 
Protein Sequence
GGASLLLLDC RPHELFESSH IETAINLAIP GLMLRRLRKG NLPIRSIIPN HADKERFATR 60
CKAATVLLYD EATAEWQPEP GAPASVLGLL LQKLRDDGCQ AYYLQGGFNK FQTEYSEHCE 120
TNVDSSSSPS SSPPTSVLGL GGLRISSDCS DGESDRELPS SATESDGSPV PSSQPAFPVQ 180
ILPYLYLGCA KDSTNLDVLG KYGIKYILNV TPNLPNAFEH GGEFTYKQIP ISDHWSQNLS 240
QFFPEAISFI GRCCVLGRGV WVHQGVCRTL GGAPA 275 
Gene Ontology
 GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
 GO:0006470; P:protein dephosphorylation; IEA:InterPro. 
Interpro
 IPR000340; Dual-sp_phosphatase_cat-dom.
 IPR020422; Dual-sp_phosphatase_subgr_cat.
 IPR024950; DUSP.
 IPR008343; MKP.
 IPR001763; Rhodanese-like_dom. 
Pfam
 PF00782; DSPc
 PF00581; Rhodanese 
SMART
 SM00450; RHOD 
PROSITE
 PS50206; RHODANESE_3
 PS50054; TYR_PHOSPHATASE_DUAL 
PRINTS
 PR01764; MAPKPHPHTASE.