CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028810
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Growth factor receptor bound protein 14 
Protein Synonyms/Alias
  
Gene Name
 Grb14 
Gene Synonyms/Alias
 mCG_22301 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
383AMDFSGEKSRVIDNPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Phosphoprotein; Receptor. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 538 AA 
Protein Sequence
MTTSLQDGQS AAGRAGAQDS PLAVQVCRVA QGKGDAQDPA QVPGLHALSP ASDATLRGAI 60
DRRKMKDLDV LEKPPIPNPF PELCCSPLTS VLSAGLFPRA NSRKKQVIKV YSEDETSRAL 120
EVPSDITARD VCQLLILKNH YVDDNSWTLF EHLSHIGLER TVEDHELPTE VLSHWGVEED 180
NKLYLRKNYA KYEFFKNPMY FFPEHMVSFA AEMNGDRSPT QILQVFLSSS TYPEIHGFLH 240
AKEQGKKSWK KAYFFLRRSG LYFSTKGTSK EPRHLQLFSE FSTSHVYMSL AGKKKHGAPT 300
PYGFCLKPNK AGGPRDLKML CAEEEQSRTC WVTAIRLLKD GMQLYQNYMH PYQGRSACNS 360
QSMSPMRSVS ENSLVAMDFS GEKSRVIDNP TEALSVAVEE GLAWRKKGCL RLGNHGSPSA 420
PSQSSAVNMA LHRSQPWFHH RISRDEAQRL IIRQGPVDGV FLVRDSQSNP RTFVLSMSHG 480
QKIKHYQIIP VEDDGELFHT LDDGHTKFTD LIQLVEFYQL NRGVLPCKLK HYCARMAV 538 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0043231; C:intracellular membrane-bounded organelle; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0005070; F:SH3/SH2 adaptor activity; IDA:MGI.
 GO:0007165; P:signal transduction; TAS:MGI. 
Interpro
 IPR015042; BPS-dom.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR000159; Ras-assoc.
 IPR000980; SH2. 
Pfam
 PF08947; BPS
 PF00169; PH
 PF00788; RA
 PF00017; SH2 
SMART
 SM00233; PH
 SM00314; RA
 SM00252; SH2 
PROSITE
 PS50003; PH_DOMAIN
 PS50200; RA
 PS50001; SH2 
PRINTS
 PR00401; SH2DOMAIN.