CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017809
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Amyloid beta A4 precursor protein-binding family B member 3 
Protein Synonyms/Alias
  
Gene Name
 Apbb3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
220FAFVAGDKDSCMLKCubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May modulate the internalization of beta-amyloid precursor protein (By similarity). 
Sequence Annotation
 DOMAIN 29 61 WW.
 DOMAIN 113 280 PID 1.
 DOMAIN 285 440 PID 2.  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 486 AA 
Protein Sequence
MLGKDYMLAI ILVNCDDDLW GDQNLEGETG LPPGWRKIRD AAGTYYWHVP SGSTQWQRPT 60
WELPGAEDPG RGTEGIWELR PPKGRSFSSL DSSLNRSNSL TWYSEDSYVR SLEPGAKCFA 120
VRSLGWVEVP EEDLAPGKSS IAVNNCIQQL AQTRNRSQPH DGTWGEGQNM LMILKKDAMS 180
LLNPLDHSLI HCQPLVHIRV WGVGSSKGRD RDFAFVAGDK DSCMLKCHVF HCDVPAKAIA 240
SALQGLCAQI LSERVGVSGE AACCSPDPIS PEDLPRQVEL LDAVSQAAQK YEALYMGILP 300
VTKAMGMDVL NEAIGTLTAR GDRKTWVPAM LSVSDSLMTA HAIQAEAGAE EEPLWQCPVR 360
LVTFIGVGRD PHTFGLIADL GCQSFQCAAF WCEPHAGGLS EAVQAACMVQ YQKCLVASAA 420
RGKAWGAQAR ARLRLKRTSS MDSPGGPLPP PLLKGGAGGA GAAPRKRGVF SFLDAFRLKP 480
SLLHMS 486 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; TAS:MGI. 
Interpro
 IPR011993; PH_like_dom.
 IPR006020; PTyr_interaction_dom.
 IPR001202; WW_dom. 
Pfam
 PF00640; PID
 PF00397; WW 
SMART
 SM00462; PTB
 SM00456; WW 
PROSITE
 PS01179; PID
 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2 
PRINTS