UniProt Accession

 BASP1_MOUSE; Q91XV3 

Genbank Protein ID

 AB046714 

Genbank Nucleotide ID

 BAB62404.1 

Protein Name

 Brain acid soluble protein 1 

Protein Synonyms/Alias

 22 kDa neuronal tissue-enriched acidic protein; Neuronal axonal membrane protein NAP-22 

Gene Name

 Basp1 

Gene Synonyms/Alias

 Nap22 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
18	GYNVNDEKAKDKDKK	acetylation	[1]
25	KAKDKDKKAEGAGTE	ubiquitination	[2]
38	TEEEGTPKESEPQAA	ubiquitination	[2]
52	AADATEVKESTEEKP	ubiquitination	[2]
58	VKESTEEKPKDAADG	ubiquitination	[2]
81	ADKAAAAKEEAPKAE	ubiquitination	[2]
146	APEEGEAKKTEAPAA	ubiquitination	[2]
147	PEEGEAKKTEAPAAA	ubiquitination	[2]
170	APAASDSKPSSAEPA	acetylation	[1, 3]
170	APAASDSKPSSAEPA	succinylation	[1]
170	APAASDSKPSSAEPA	ubiquitination	[2]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

 MOD_RES 31 31 Phosphothreonine.
 MOD_RES 36 36 Phosphothreonine.
 MOD_RES 92 92 Phosphoserine.
 MOD_RES 128 128 Phosphoserine.
 MOD_RES 160 160 Phosphoserine.
 MOD_RES 167 167 Phosphoserine.
 MOD_RES 169 169 Phosphoserine (By similarity).
 MOD_RES 173 173 Phosphoserine.
 MOD_RES 218 218 Phosphoserine.
 LIPID 2 2 N-myristoyl glycine (By similarity).  

Keyword

 Cell membrane; Cell projection; Complete proteome; Direct protein sequencing; Lipoprotein; Membrane; Myristate; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 226 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.
 GO:0016607; C:nuclear speck; IDA:UniProtKB.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0008180; C:signalosome; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
 GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
 GO:0072112; P:glomerular visceral epithelial cell differentiation; IDA:UniProtKB.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. 

Interpro

 IPR008408; BASP1. 

Pfam

 PF05466; BASP1 

SMART

  

PROSITE

  

PRINTS