| Tag | Content |
|---|
| CPLM ID | CPLM-002845 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Regulatory protein SWI6 |
Protein Synonyms/Alias | Cell-cycle box factor subunit SWI6; MBF subunit P90; Trans-acting activator of HO endonuclease gene |
Gene Name | SWI6 |
Gene Synonyms/Alias | YLR182W; L9470.8 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 515 | DFGAGTSKLQNTNGG | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Part of a complex involved in cell-cycle-dependent transcription. SWI4 and SWI6 are required for formation of the cell-cycle box factor-DNA complex. The repeated element in the upstream region of HO (5'-CACGAAAA-3') is called the cell cycle box (CCB). |
Sequence Annotation | REPEAT 318 346 ANK 1.
REPEAT 347 383 ANK 2.
REPEAT 384 469 ANK 3.
REPEAT 470 498 ANK 4.
REPEAT 499 514 ANK 5.
MOD_RES 149 149 Phosphoserine.
MOD_RES 160 160 Phosphoserine; by CDC28.
MOD_RES 176 176 Phosphoserine.
MOD_RES 179 179 Phosphothreonine.
MOD_RES 182 182 Phosphothreonine.
MOD_RES 547 547 Phosphoserine. |
Keyword | 3D-structure; Activator; ANK repeat; Complete proteome; Cytoplasm; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 803 AA |
Protein Sequence | MALEEVVRYL GPHNEIPLTL TRDSETGHFL LKHFLPILQQ YHDTGNINET NPDSFPTDEE 60
RNKLLAHYGI AVNTDDRGEL WIELEKCLQL LNMLNLFGLF QDAFEFEEPE TDQDEEDPSH 120
SKLPENKTKS ENSKDNISSK RINNLQDMSL DSDAHRELGS PLKKLKIDTS VIDAESDSTP 180
NTARGKPNDD INKGPSGDNE NNGTDDNDRT AGPIITFTHD LTSDFLSSPL KIMKALPSPV 240
VNDNEQKMKL EAFLQRLLFP EIQEMPTSLN NDSSNRNSEG GSSNQQQQHV SFDSLLQEVN 300
DAFPNTQLNL NIPVDEHGNT PLHWLTSIAN LELVKHLVKH GSNRLYGDNM GESCLVKAVK 360
SVNNYDSGTF EALLDYLYPC LILEDSMNRT ILHHIIITSG MTGCSAAAKY YLDILMGWIV 420
KKQNRPIQSG TNEKESKPND KNGERKDSIL ENLDLKWIIA NMLNAQDSNG DTCLNIAARL 480
GNISIVDALL DYGADPFIAN KSGLRPVDFG AGTSKLQNTN GGDENSKMVS KGDYDGQKNG 540
KAKKIRSQLL KNPPETTSLI NDVQNLLNSI SKDYENETVQ YNEKLEKLHK ELNEQREELA 600
NSREQLANVK QLKDEYSLMQ EQLTNLKAGI EEEEESFREE SKKLGIIADE SSGIDWDSSE 660
YDADEPFKVE FLSDFLEDKL QKNYEGDISK LLEAESKEQI MEQIRNQLPA EKIQSMLPPT 720
VLLKARINAY KRNDKHLTNV LDTISTKQSE LENKFRRVLS LCLKIDENKV DNMLDGLLQA 780
ISSEDPQDID TDEMQDFLKK HAS 803 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:SGD. GO:0030907; C:MBF transcription complex; IDA:SGD. GO:0033309; C:SBF transcription complex; IDA:SGD. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0001105; F:RNA polymerase II transcription coactivator activity; IMP:SGD. GO:0010845; P:positive regulation of reciprocal meiotic recombination; IMP:SGD. GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD. GO:0071931; P:positive regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |