CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022737
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Endomucin 
Protein Synonyms/Alias
 Endomucin-1/2; Mucin-14; MUC-14 
Gene Name
 Emcn 
Gene Synonyms/Alias
 Muc14 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
244SVKLLTVKTISHESGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Endothelial sialomucin, also called endomucin or mucin- like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (By similarity). 
Sequence Annotation
 CARBOHYD 28 28 N-linked (GlcNAc...) (Potential).
 CARBOHYD 101 101 N-linked (GlcNAc...) (Potential).
 CARBOHYD 119 119 N-linked (GlcNAc...) (Potential).
 CARBOHYD 127 127 N-linked (GlcNAc...) (Potential).
 CARBOHYD 131 131 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 261 AA 
Protein Sequence
MRLLQATVLF FLLSNSLCHS EDGKDVQNDS IPTPAETSTT KASVTIPGIV SVTNPNKPAD 60
GTPPEGTTKS DVSQTSLVTT INSLTTPKHE VGTTTEGPLR NESSTMKITV PNTPTSNANS 120
TLPGSQNKTE NQSSIRTTEI SVTTQLLDAL PKITATSSAS LTTAHTMSLL QDTEDRKIAT 180
TPSTTPSYSS IILPVVIALV VITLLVFTLV GLYRICWKRD PGTPENGNDQ PQSDKESVKL 240
LTVKTISHES GEHSAQGKTK N 261 
Gene Ontology
 GO:0016021; C:integral to membrane; ISA:MGI.
 GO:0005886; C:plasma membrane; ISS:HGNC.
 GO:0030246; F:carbohydrate binding; ISS:HGNC.
 GO:0001525; P:angiogenesis; ISS:HGNC.
 GO:0016337; P:cell-cell adhesion; ISS:HGNC.
 GO:0030155; P:regulation of cell adhesion; ISS:HGNC. 
Interpro
 IPR010740; Endomucin. 
Pfam
 PF07010; Endomucin 
SMART
  
PROSITE
  
PRINTS