UniProt Accession

 RLA0_YEAST; P05317; D6VYX8 

Genbank Protein ID

 X06959; D00529; X13328; M26506; M37326; U19028; BK006945 

Genbank Nucleotide ID

 CAA30029.1; BAA00415.1; CAA31703.1; AAA34730.1; AAA34729.1; AAB67258.1; DAA09644.1 

Protein Name

 60S acidic ribosomal protein P0 

Protein Synonyms/Alias

 A0; L10E 

Gene Name

 RPP0 

Gene Synonyms/Alias

 L10E; RPA0; RPL10E; RPLA0; YLR340W; L8300.8 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
14	KKAEYFAKLREYLEE	acetylation	[1]
14	KKAEYFAKLREYLEE	ubiquitination	[2, 3]
55	RAVVLMGKNTMVRRA	ubiquitination	[3]
75	SDLPDFEKLLPFVKG	ubiquitination	[2, 3]
81	EKLLPFVKGNVGFVF	ubiquitination	[3]
97	NEPLTEIKNVIVSNR	ubiquitination	[2, 3]
132	NTGMEPGKTSFFQAL	acetylation	[1]
132	NTGMEPGKTSFFQAL	ubiquitination	[3]
144	QALGVPTKIARGTIE	acetylation	[1]
144	QALGVPTKIARGTIE	ubiquitination	[2, 3, 4]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [3] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [4] Systematic approach for validating the ubiquitinated proteome.
 Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
 Anal Chem. 2008 Jun 1;80(11):4161-9. [PMID: 18433149] 

Functional Description

 Ribosomal protein P0 is the functional equivalent of E.coli protein L10. 

Sequence Annotation

 REGION 199 230 Interaction with P1A-P2B.
 REGION 231 258 Interaction with P1B-P2A.
 MOD_RES 68 68 Phosphoserine.
 MOD_RES 302 302 Phosphoserine; by CK2.  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 312 AA 

Protein Sequence

Gene Ontology

 GO:0030686; C:90S preribosome; IDA:SGD.
 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0070180; F:LSU rRNA binding; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; TAS:SGD.
 GO:0002181; P:cytoplasmic translation; TAS:SGD.
 GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.
 GO:0006414; P:translational elongation; ISS:SGD. 

Interpro

 IPR001790; Ribosomal_L10/acidic_P0.
 IPR001813; Ribosomal_L10/L12. 

Pfam

 PF00428; Ribosomal_60s
 PF00466; Ribosomal_L10 

SMART

  

PROSITE

  

PRINTS