CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037359
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sodium bicarbonate cotransporter 3 
Protein Synonyms/Alias
  
Gene Name
 SLC4A7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
514HDVAYKAKDRNDLLSubiquitination[1]
599GGLILDIKRKAPFFLubiquitination[1]
863TKRYFPTKVRSTISDubiquitination[1]
1195QIPVKALKYSVDPSIubiquitination[1]
1216MAKTAQWKALSMNTEubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1259 AA 
Protein Sequence
MEADGAGEQM RPLLTRVTSR GPDEEAVVDL GKTSSTVNTK FEKEELESHR AVYIGVHVPF 60
SKESRRRHRH RGHKHHHRRR KDKESDKEDG RESPSYDTPS QRVQFILGTE DDDEEHIPHD 120
LFTEMDELCY RDGEEYEWKE TARWLKFEED VEDGGDRWSK PYVATLSLHS LFELRSCILN 180
GTVMLDMRAS TLDEIADMVL DNMIASGQLD ESIRENVREA LLKRHHHQNE KRFTSRIPLV 240
RSFADIGKKH SDPHLLERNG EGLSASRHSL RTGLSASNLS LRGESPLSLL LGHLLPSSRA 300
GTPAGSRCTT PVPTPQNSPP SSPSISRLTS RSSQESQRQA PELLVSPASD DIPTVVIHPP 360
EEDLEAALKG EEQKNEENVD LTPGILASPQ SAPGNLDNSK SGEIKGNGSG GSRENSTVDF 420
SKVDMNFMRK IPTGAEASNV LVGEVDFLER PIIAFVRLAP AVLLTGLTEV PVPTRFLFLL 480
LGPAGKAPQY HEIGRSIATL MTDEIFHDVA YKAKDRNDLL SGIDEFLDQV TVLPPGEWDP 540
SIRIEPPKSV PSQEKRKIPV FHNGSTPTLG ETPKEAAHHA GPELQRTGRL FGGLILDIKR 600
KAPFFLSDFK DALSLQCLAS ILFLYCACMS PVITFGGLLG EATEGRISAI ESLFGASLTG 660
IAYSLFAGQP LTILGSTGPV LVFEKILYKF CRDYQLSYLS LRTSIGLWTS FLCIVLVATD 720
ASSLVCYITR FTEEAFAALI CIIFIYEALE KLFDLGETYA FNMHNNLDKL TSYSCVCTEP 780
PNPSNETLAQ WKKDNITAHN ISWRNLTVSE CKKLRGVFLG SACGHHGPYI PDVLFWCVIL 840
FFTTFFLSSF LKQFKTKRYF PTKVRSTISD FAVFLTIVIM VTIDYLVGVP SPKLHVPEKF 900
EPTHPERGWI ISPLGDNPWW TLLIAAIPAL LCTILIFMDQ QITAVIINRK EHKLKKGAGY 960
HLDLLMVGVM LGVCSVMGLP WFVAATVLSI SHVNSLKVES ECSAPGEQPK FLGIREQRVT 1020
GLMIFILMGL SVFMTSVLKF IPMPVLYGVF LYMGVSSLKG IQLFDRIKLF GMPAKHQPDL 1080
IYLRYVPLWK VHIFTVIQLT CLVLLWVIKV SAAAVVFPMM VLALVFVRKL MDLCFTKREL 1140
SWLDDLMPES KKKKEDDKKK KEKEEAERML QDDDDTVHLP FEGGSLLQIP VKALKYSVDP 1200
SIVNISDEMA KTAQWKALSM NTENAKVTRS NMSPDKPVSV KISFEDEPRK KYVDAETSL 1259 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro. 
Interpro
 IPR013769; Band3_cytoplasmic_dom.
 IPR011531; HCO3_transpt_C.
 IPR003020; HCO3_transpt_euk.
 IPR016152; PTrfase/Anion_transptr. 
Pfam
 PF07565; Band_3_cyto
 PF00955; HCO3_cotransp 
SMART
  
PROSITE
  
PRINTS
 PR01231; HCO3TRNSPORT.