CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027029
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG8728 
Protein Synonyms/Alias
 GH09295p; LD05680p 
Gene Name
 CG8728-RA 
Gene Synonyms/Alias
 CG8728; Dmel_CG8728 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
57RTSDGPQKVNTPSKEacetylation[1]
158PNKDAILKELEKNGGacetylation[1]
396MYSRLYTKVLNRYHWacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 556 AA 
Protein Sequence
MMNGRSIGML KKLRHTWRTF PRLMATKVTS LGGDEVGSGT GIGQITGGVR TSDGPQKVNT 60
PSKEIVTHLP PLTEPLPNLP EAVYAAPLAE SAITKVTTLP NGLRIASEPR YGQFCTVGLV 120
IDSGPRYEVA YPSGVSHFLE KLAFNSTVNF PNKDAILKEL EKNGGICDCQ SSRDTLIYAA 180
SIDSRAIDSV TRLLADVTLR PTLSDQEVSL ARRAVNFELE TLGMRPEQEP ILMDMIHAAA 240
FRDNTLGLPK LCPLENLDHI NRNVLMNYLK YHHSPKRMVI AGVGVDHDEL VSHVQRYFVE 300
DKAIWETEAL EDSGPKQVDT SIAQYTGGLV KEQCEIPIYA AAGLPELAHV ILGFEGCSHQ 360
DKDFVPLCVL NIMMGGGGSF SAGGPGKGMY SRLYTKVLNR YHWMYSATAY NHAYGDCGLF 420
CVHGSAPPQH MNDMVEVLTR EMMGMAAEPG REELMRSKIQ LQSMLLMNLE SRPVVFEDVG 480
RQVLVTGQRK RPQHFIKEIE SVTAADIQRV AQRLLSSPPS VAARGDIHNL PEMSHITNAV 540
SGSGRTGLGR RLSLFK 556 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR011249; Metalloenz_LuxS/M16.
 IPR011237; Pept_M16_dom.
 IPR011765; Pept_M16_N.
 IPR001431; Pept_M16_Zn_BS.
 IPR007863; Peptidase_M16_C. 
Pfam
 PF00675; Peptidase_M16
 PF05193; Peptidase_M16_C 
SMART
  
PROSITE
 PS00143; INSULINASE 
PRINTS