CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029806
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Astrocytic phosphoprotein PEA-15 
Protein Synonyms/Alias
 Phosphoprotein enriched in astrocytes 15, isoform CRA_b; cDNA FLJ38560 fis, clone HCHON2003642, highly similar to Astrocytic phosphoprotein PEA-15 
Gene Name
 PEA15 
Gene Synonyms/Alias
 hCG_39732 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
56KEDIPSEKSEEITTGacetylation[1]
119EEDELDTKLTRIPSAubiquitination[2, 3]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 151 AA 
Protein Sequence
MEDEGNKLCQ APPWPGQTSP VMAEYGTLLQ DLTNNITLED LEQLKSACKE DIPSEKSEEI 60
TTGSAWFSFL ESHNKLDKDN LSYIEHIFEI SRRPDLLTMV VDYRTRVLKI SEEDELDTKL 120
TRIPSAKKYK DIIRQPSEEE IIKLAPPPKK A 151 
Gene Ontology
 GO:0042981; P:regulation of apoptotic process; IEA:InterPro. 
Interpro
 IPR011029; DEATH-like_dom.
 IPR001875; DED. 
Pfam
 PF01335; DED 
SMART
 SM00031; DED 
PROSITE
 PS50168; DED 
PRINTS