CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038336
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Alpha-adducin 
Protein Synonyms/Alias
  
Gene Name
 Add1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
148GEKLLRCKLAAFYRLubiquitination[1]
288EEKILIQKNLGPKSKacetylation[2]
288EEKILIQKNLGPKSKubiquitination[1]
497VPLNTNPKEVQEMRNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 660 AA 
Protein Sequence
MNGDTRAAVV TSPPPTTAPH KERYFDRVDE NNPEYLRERN MAPDLRQDFN MMEQKKRVSM 60
ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTA SVPNVYPAAP QGGMAALNMS 120
LGMVTPVNDL RGSDSIAYDK GEKLLRCKLA AFYRLADLFG WSQLIYNHIT TRVNSEQEHF 180
LIVPFGLLYS EVTASSLVKV NLQGDIVDRG STNLGVNQAG FTLHSAVYAA RPDAKCIVHI 240
HTPAGAAVSA MKCGLLPISP EALSLGDVAY HDYHGILVDE EEKILIQKNL GPKSKVLILR 300
NHGLVSVGES VEEAFYYIHN LVVACEIQVR TLASAGGPDN LVLLDPGKYK AKSRSPGTPA 360
GEGSGSPPKW QIGEQEFEAL MRMLDNLGYR TGYPYRYPAL RERSKKYSDV EVPASVTGHS 420
FASDGDSGTC SPLRHSFQKQ QREKTRWLHS GRGDDASEEG QNGSSPKSKT KWTKEDGHRT 480
STSAVPNLFV PLNTNPKEVQ EMRNKIREQN LQDIKTAGPQ SQVLCGVMMD RSLVQDAPLS 540
DCTETIEGLA EQTFSPAKSV SFRKGELVTA SKAIIEKEYQ PHVIVSTTGP NPFNTLTDRE 600
LEEYRREVER KQKGSEENLD ETREQKEKSP PDQSAVPNTP PSTPVKLEEG DGCAKEYLLP 660 
Gene Ontology
 GO:0005856; C:cytoskeleton; IDA:MGI.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0005198; F:structural molecule activity; IDA:MGI.
 GO:0000902; P:cell morphogenesis; IMP:MGI.
 GO:0006884; P:cell volume homeostasis; IMP:MGI.
 GO:0030218; P:erythrocyte differentiation; IMP:MGI.
 GO:0020027; P:hemoglobin metabolic process; IMP:MGI.
 GO:0048873; P:homeostasis of number of cells within a tissue; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0035264; P:multicellular organism growth; IMP:MGI. 
Interpro
 IPR001303; Aldolase_II/adducin_N. 
Pfam
 PF00596; Aldolase_II 
SMART
 SM01007; Aldolase_II 
PROSITE
  
PRINTS