UniProt Accession

 A2AI16_MOUSE; A2AI16 

Genbank Protein ID

 AL732309 

Genbank Nucleotide ID

  

Protein Name

 Glutamate receptor ionotropic, NMDA 1 

Protein Synonyms/Alias

  

Gene Name

 Grin1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
881	AAVNVWRKNLQQYHP	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Cell junction; Cell membrane; Complete proteome; Ion channel; Ion transport; Ligand-gated ion channel; Membrane; Postsynaptic cell membrane; Receptor; Reference proteome; Synapse; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 906 AA 

Protein Sequence

Gene Ontology

 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0017146; C:N-methyl-D-aspartate selective glutamate receptor complex; IPI:MGI.
 GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
 GO:0014069; C:postsynaptic density; IDA:MGI.
 GO:0045211; C:postsynaptic membrane; IDA:MGI.
 GO:0008021; C:synaptic vesicle; IDA:MGI.
 GO:0005262; F:calcium channel activity; IDA:MGI.
 GO:0005509; F:calcium ion binding; IDA:MGI.
 GO:0005516; F:calmodulin binding; IDA:MGI.
 GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.
 GO:0004972; F:N-methyl-D-aspartate selective glutamate receptor activity; IDA:MGI.
 GO:0008344; P:adult locomotory behavior; IMP:MGI.
 GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.
 GO:0021987; P:cerebral cortex development; IMP:MGI.
 GO:0001661; P:conditioned taste aversion; IMP:MGI.
 GO:0007616; P:long-term memory; IMP:MGI.
 GO:0060179; P:male mating behavior; IMP:MGI.
 GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.
 GO:0008355; P:olfactory learning; IMP:MGI.
 GO:0021586; P:pons maturation; IMP:MGI.
 GO:0043065; P:positive regulation of apoptotic process; IGI:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0060134; P:prepulse inhibition; IMP:MGI.
 GO:0050770; P:regulation of axonogenesis; IMP:MGI.
 GO:0048814; P:regulation of dendrite morphogenesis; IMP:MGI.
 GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:MGI.
 GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.
 GO:0043576; P:regulation of respiratory gaseous exchange; IMP:MGI.
 GO:0051963; P:regulation of synapse assembly; IMP:MGI.
 GO:0007585; P:respiratory gaseous exchange; IMP:MGI.
 GO:0001975; P:response to amphetamine; IMP:MGI.
 GO:0043278; P:response to morphine; IMP:MGI.
 GO:0019233; P:sensory perception of pain; IMP:MGI.
 GO:0035176; P:social behavior; IMP:MGI.
 GO:0001967; P:suckling behavior; IMP:MGI.
 GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.
 GO:0008542; P:visual learning; IMP:MGI. 

Interpro

 IPR001828; ANF_lig-bd_rcpt.
 IPR018882; CaM-bd_C0_NMDA_rcpt_NR1.
 IPR019594; Glu_rcpt_Glu/Gly-bd.
 IPR001320; Iontro_glu_rcpt.
 IPR001508; NMDA_rcpt.
 IPR001638; SBP_bac_3. 

Pfam

 PF01094; ANF_receptor
 PF10562; CaM_bdg_C0
 PF00060; Lig_chan
 PF00497; SBP_bac_3 

SMART

 SM00918; Lig_chan-Glu_bd
 SM00079; PBPe 

PROSITE

  

PRINTS

 PR00177; NMDARECEPTOR.