UniProt Accession

 K1B27_MOUSE; Q9JM71; A2RSF8 

Genbank Protein ID

 AB039275; BC132090; BC132665 

Genbank Nucleotide ID

 BAA92318.1; AAI32091.1; AAI32666.1 

Protein Name

 Kallikrein 1-related peptidase b27 

Protein Synonyms/Alias

 Glandular kallikrein K27; mGK-27; Tissue kallikrein 27; mKlk27 

Gene Name

 Klk1b27 

Gene Synonyms/Alias

 Klk-27; Klk27 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
30	SRIIGGFKCKKNSQP	acetylation	[1]
32	IIGGFKCKKNSQPWH	acetylation	[1]

Reference

 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 

Functional Description

 Serine protease with chymotrypsin-like cleavage specificity. Shows activity towards casein, gelatin, IGFBP3 and fibronectin but not towards laminin or collagens I and IV. Does not hydrolyze kininogin to release Lys-bradykinin. 

Sequence Annotation

 DOMAIN 25 260 Peptidase S1.
 ACT_SITE 65 65 Charge relay system (By similarity).
 ACT_SITE 122 122 Charge relay system (By similarity).
 ACT_SITE 215 215 Charge relay system (By similarity).
 CARBOHYD 69 69 N-linked (GlcNAc...) (Potential).
 CARBOHYD 105 105 N-linked (GlcNAc...) (Potential).
 DISULFID 31 175 By similarity.
 DISULFID 50 66 By similarity.
 DISULFID 154 221 By similarity.
 DISULFID 186 200 By similarity.
 DISULFID 211 236 By similarity.  

Keyword

 Complete proteome; Disulfide bond; Glycoprotein; Hydrolase; Protease; Reference proteome; Serine protease; Signal; Zymogen. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 263 AA 

Protein Sequence

Gene Ontology

 GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
 GO:0006508; P:proteolysis; IDA:UniProtKB. 

Interpro

 IPR001254; Peptidase_S1.
 IPR018114; Peptidase_S1_AS.
 IPR001314; Peptidase_S1A.
 IPR009003; Trypsin-like_Pept_dom. 

Pfam

 PF00089; Trypsin 

SMART

 SM00020; Tryp_SPc 

PROSITE

 PS50240; TRYPSIN_DOM
 PS00134; TRYPSIN_HIS
 PS00135; TRYPSIN_SER 

PRINTS

 PR00722; CHYMOTRYPSIN.