CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038866
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 PH domain leucine-rich repeat protein phosphatase 1 
Protein Synonyms/Alias
  
Gene Name
 Phlpp1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
212RLLQLGHKGGGVVKVubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1696 AA 
Protein Sequence
MEPAAAAPAQ RLADPTGEDR APAAAAAAEG GRSPDSVLSA AAPSGNGGAA REEAPCEAPR 60
GLPGRAGGTG RRRRRGVPQP AAGGAAPVTA AGGGANSLLL RRGRLKRNLS AAASSSSSPS 120
SASSAAGGLP ASCSASASLC TRSLDRKTLL QKHRQLLQLQ PSDRDWVRHQ LQRGCVHVFD 180
RHMASSYLRP VLCTLDTTAA EVAARLLQLG HKGGGVVKVL GHGPPPAAAP AASDQTPATE 240
LGRDVEPPPS SSTVGAVRGP ARAPPADLPL PGGAWTRCAP RVNPAPSDSS PGELFAGGPC 300
SPSRAPRPAS DTESFSLSPS AESVSDRLDP YSSGGGSSSS SEELEADPAT VLTGPSGPPH 360
HPVRSSQPRP PSPKTSALLQ PKAPTGVDGT GLVVGEGPGD DKAVAAAAPG VPLWTPGRIR 420
ETVQKTSSPP SLYVQLHGET TRRLEADEKP LQIQNDYLFQ LGFGELWRVQ EEGMDSEIGC 480
LIRFYAGKPH STGSSERIQL SGMYNVRKGK MQLPVNRWTR RQVILCGTCL IVSSVKDSSS 540
GKMHVLPLIG GKVEEVKKHQ HCLAFSSSGP QSQTYYICFD TFTEYLRWLR QVSKVASQRI 600
SSVDLSCCSL EHLPANLFYS QDLTHLNLKQ NFLRQNPSLP AARGLGELQR FTKLKSLNLS 660
NNHLGAFPSA VCSIPTLAEL NVSCNALREV PAAVGAMQNL QTFLLDGNFL QSLPAELENM 720
HQLSYLGLSF NEFTDIPEVL EKLTAVDKLC MAGNCMETLR LQALRRMPHI KHVDLRLNIL 780
RKLITDEVDF LQHVTQLDLR DNKLGDLDAM IFNNIEVLHC ERNQLVTLNI CGYFLKALYA 840
SSNELVQLDV YPVPNYLSYM DVSRNCLESV PEWVCESRKL EVLDIGHNQI CELPARLFCN 900
SSLRKLLAGH NRLARLPERL ERTSVEVLDV QHNQIIELPP NLLMKADSLR FLNASANKLE 960
TLPPATLSEE TSSILQELYL TNNSLTDKCV PLLTGHPRLK ILHMAYNRLQ SFPASKMAKL 1020
EELEEIDISG NKLKAIPTTI MNCRRMHTVI AHSNCIEVFP EVMQLPEVKC VDLSCNELSE 1080
ITLPENLPPK LQELDLTGNP RLALDHKSLE LLNNIRCFKI DQPSAGDASG APAVWSHGYT 1140
EASGVKNKLC VAALSVNNFR DNREALYGVF DGDRNVEVPY LLQCTMSDIL AEELQKTKNE 1200
EEYMVNTFIV MQRKLGTAGQ KLGGAAVLCH IRHDPVDLGG SFTLTSANVG KCQTVLCRNG 1260
KPLSLSRSYT MSCEEERKRI KQHKAIITED GKVNGVTEST RILGYTFLHP SVVPRPHVQS 1320
VLLTPQDEFF ILGSKGLWDS LSIEEAVEAV RNVPDALAAA KKLCTLAQSY GCHDSISAVV 1380
VQLSVTEDSF CCCELSVGGS MPPPSPGIFP PSVSMVIKDR PSDGLGVPSS SSGMASEISS 1440
ELSTSEMSSE VGSTASDEPP SGALSESSPA YPSEQRCMLH PVCLSNSFQR QLSSATFSSA 1500
FSDNGLDSDD EEPIEGVFSN GSRVEVEVDI HCSRAKEKER QQHLLQVPAE ASDEGIVISA 1560
NEDESGLSKK TDISAVGTIG RRRANGSVAP QERSHNVIEV ATDAPLRKPG GYFAAPAQPD 1620
PDDQFIIPPE LEEEVKEIMK HHQEQQQQQQ QQQQQQQQQQ QPPPPPQPPQ AQAQAQAQAQ 1680
RPFQMDHLPD CYDTPL 1696 
Gene Ontology
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR001611; Leu-rich_rpt.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR001932; PP2C-like. 
Pfam
 PF00560; LRR_1
 PF00481; PP2C 
SMART
 SM00233; PH
 SM00332; PP2Cc 
PROSITE
 PS51450; LRR
 PS50003; PH_DOMAIN 
PRINTS