CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014790
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 512 
Protein Synonyms/Alias
  
Gene Name
 Znf512 
Gene Synonyms/Alias
 Kiaa1805; Zfp512 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
109AKGKRNVKQEEDEDYacetylation[1]
287KEASELEKLALKCHHacetylation[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
 May be involved in transcriptional regulation (By similarity). 
Sequence Annotation
 ZN_FING 200 223 C2H2-type 1.
 ZN_FING 290 313 C2H2-type 2.
 ZN_FING 442 465 C2H2-type 3.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 562 AA 
Protein Sequence
MSSRLGAVTA TPGPTSLKQQ RSTRIVGAKN NRAQCSIKDN SFQYTIPHED SLSGSSSASS 60
CEPVSDFTAT LRKSTYWMKM RRIKPAATSQ VEGAGEKEKE RAKGKRNVKQ EEDEDYRELP 120
QKKHKLYGRK QRPKAQPHPK PQARRVRKEP PVYAAGSMEE KWYLEIMDKG SVSCPTCQAV 180
GRKTIEGLKK HMENCKQEMF TCHHCGKQLH SLAGMKYHVM ANHNSLPILK AGDEVDEPSE 240
RERLRTVLKR MGKLRCMRES CSSTFTSIMG YLYHVRKCGK EASELEKLAL KCHHCGKPYR 300
SKAGLAYHMR SEHGPVFFPE SEQPDCLKEM SLEAKGGGRV QRRSAKIAVY HLQELASAEL 360
TKEWPKRKVL QDLVPDDRKL KYTRPGLPTF SQEVLHKWKT DIKKYHRIQC PNQGCEAVYS 420
SVSGLKAHLG SCTLGTFVAG KYKCLLCEKE FVSESGVKYH INSVHAEDWF VVNPTTTKSF 480
EKLMKIKQRQ QEEEKQRQQH GRRRSLRRQQ QPCMEPPESQ LEPKAGKEQG GNEELVGPDP 540
EPVPAQPQKA EPAKTTHKRG RK 562 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 
Pfam
 PF00096; zf-C2H2 
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS