CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025108
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Fibrinogen, B beta polypeptide, isoform CRA_a 
Protein Synonyms/Alias
  
Gene Name
 Fgb 
Gene Synonyms/Alias
 mCG_17068 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
43HRPVDRRKEEPPSLRubiquitination[1]
237ECEEIIRKGGETSEMubiquitination[1]
254IQPDTSIKPYRVYCDubiquitination[1]
263YRVYCDMKTENGGWTubiquitination[1]
303IATNEDAKKYCGLPGubiquitination[1]
343DWKGDKVKAHYGGFTubiquitination[1]
364KYQVSVNKYKGTAGNubiquitination[1]
416DPRKQCSKEDGGGWWubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Disulfide bond. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 481 AA 
Protein Sequence
MRHLWLLLLL CVFSVQTQAA DDDYDEPTDS LDARGHRPVD RRKEEPPSLR PAPPPISGGG 60
YRARPAKATA NQKKVERRPP DAGGCLHADT DMGVLCPTGC TLQQTLLNQE RPIKSSIAEL 120
NNNIQSVSDT SSVTFQYLTL LKDMWKKKQA QVKENENVIN EYSSILEDQR LYIDETVNDN 180
IPLNLRVLRS ILEDLRSKIQ KLESDISAQM EYCRTPCTVS CNIPVVSGKE CEEIIRKGGE 240
TSEMYLIQPD TSIKPYRVYC DMKTENGGWT VIQNRQDGSV DFGRKWDPYK KGFGNIATNE 300
DAKKYCGLPG EYWLGNDKIS QLTRMGPTEL LIEMEDWKGD KVKAHYGGFT VQNEASKYQV 360
SVNKYKGTAG NALMDGASQL VGENRTMTIH NGMFFSTYDR DNDGWVTTDP RKQCSKEDGG 420
GWWYNRCHAA NPNGRYYWGG LYSWDMSKHG TDDGVVWMNW KGSWYSMRRM SMKIRPFFPQ 480
Q 481 
Gene Ontology
 GO:0072562; C:blood microparticle; IEA:Compara.
 GO:0005938; C:cell cortex; IDA:MGI.
 GO:0009897; C:external side of plasma membrane; IEA:Compara.
 GO:0005577; C:fibrinogen complex; IEA:InterPro.
 GO:0031091; C:platelet alpha granule; IEA:Compara.
 GO:0030168; P:platelet activation; IEA:InterPro.
 GO:0051258; P:protein polymerization; IEA:InterPro.
 GO:0051592; P:response to calcium ion; IEA:Compara.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR014716; Fibrinogen_a/b/g_C_1.
 IPR014715; Fibrinogen_a/b/g_C_2.
 IPR002181; Fibrinogen_a/b/g_C_dom.
 IPR012290; Fibrinogen_a/b/g_coil_dom.
 IPR020837; Fibrinogen_CS. 
Pfam
 PF08702; Fib_alpha
 PF00147; Fibrinogen_C 
SMART
 SM00186; FBG 
PROSITE
 PS00514; FIBRINOGEN_C_1
 PS51406; FIBRINOGEN_C_2 
PRINTS