| Tag | Content |
|---|
| CPLM ID | CPLM-008653 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | GTPase-activating protein GYP2 |
Protein Synonyms/Alias | MAC1-dependent regulator; Protein MIC1 |
Gene Name | MDR1 |
Gene Synonyms/Alias | GYP2; MIC1; YGR100W; G5717 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 210 | PGNPTMVKEKAKLRL | ubiquitination | [1] | | 942 | SANSSEEKSNLIEFE | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Stimulates specifically the GTPase activity of SEC4, YPT6 and YPT36. Inactivates YPT6 during recycling between the endosome and the Golgi compartments. |
Sequence Annotation | DOMAIN 29 116 GRAM.
DOMAIN 244 432 Rab-GAP TBC.
DOMAIN 602 637 EF-hand 1.
DOMAIN 638 673 EF-hand 2.
MOD_RES 764 764 Phosphoserine.
MOD_RES 871 871 Phosphoserine. |
Keyword | Complete proteome; Cytoplasm; GTPase activation; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 950 AA |
Protein Sequence | MSFFDSLRQK APFLDKLADS FTPTLTRDEK FRLKYKLPAN ENILEDTNAE VSFATSIKDG 60
KGHSDRVNNK GRKTAYVYSG RLFLTPHFLV FRDAFDHSSC VLILNISTIK RVERSPSESY 120
EFALLVTLYT GAKVLIQFIG IRYRSEQFCD KLKLNLKENI PNAKTLPAFL ETSYSEFLIA 180
KNILGKKDIT VPRAGLGQHF KYPGNPTMVK EKAKLRLWFD YFRENGRNLA VVQTPMFRKL 240
IRIGVPNRMR GEIWELCSGA MYMRYANSGE YERILNENAG KTSQAIDEIE KDLKRSLPEY 300
SAYQTEEGIQ RLRNVLTAYS WKNPDVGYCQ AMNIVVAGFL IFMSEEQAFW CLCNLCDIYV 360
PGYYSKTMYG TLLDQRVFES FVEDRMPVLW EYILQHDIQL SVVSLPWFLS LFFTSMPLEY 420
AVRIMDIFFM NGSITLFQVA LAVLKINADD ILQADDDGMF IAIIKHYFQT LGQSAHPDSS 480
DIKYRQITKF QELLVTAFKE FSVISEEMAM HARHKYEKGI FQNIETFMKR TQLRHMPKTF 540
NLSSDDLSNI YDMFYQSIET YKISMGTGSS NMGFEVFIQF LSKFCDSCRP CEKDKDPAFR 600
KQKRNFLQRL FDNWDSAHIG ELTLNDVVTG LDKLVTVDLL QAINYFFSLY DTDGDGELHR 660
EEVLQLSEGL LLLTEPWKSG RYVDLLTKKR IEDDIAENII KESGGEIATM NQIELPTGVT 720
IDEEKYKVEQ AERYLKAASN FLQRSFEYAK AVDLAEEVNL IDLSDDEGEE KRTVKQKQLE 780
SIKANAALDP THPKVIDLPT FRMIILADET YELFFSNTLR SSVHVDEHVN IDNKNKVLRS 840
MFDGILADGK RVAEQVRRRV DSVATRSSIA SVESTPTAAA SSITTKEEKY DDLDDFTSEH 900
QPENEELLQS SWFEIDDANE TSTKAIQERS FEPLSANSSE EKSNLIEFEA 950 |
Gene Ontology | |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |