CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025553
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytosolic alpha-D-mannosidase 
Protein Synonyms/Alias
 Mannosidase, alpha, class 2C, member 1 
Gene Name
 Man2c1 
Gene Synonyms/Alias
 mCG_141875 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
8MAAAPFLKHWRTTFEubiquitination[1]
749DYHLETRKPVLGQAGubiquitination[1]
811HEAHKFLKVEFPARIubiquitination[1]
1019SLQDNRLKLTFSPFQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1039 AA 
Protein Sequence
MAAAPFLKHW RTTFERVEKF VSPIYFTDCN LRGRLFGDSC SVTLSSFLTP ERLPYEKAVQ 60
QNFSPAQVGD SFGPTWWTCW FRVELVIPEV WVGQEVHLCW ESDGESLVWR DGEPVQGLTK 120
EGEKTSYVLS ERLRASDPRS LTLYVEVACN GLLGAGKGSM IAAPDPEKMF QLSQAKLAVF 180
HRDVHSLLVD LELLLGVAKG LGEDSQRSFQ ALHTANQMVN ICDPAQPETY PAAKALASKF 240
FGQHGGESQH TIHAMGHCHI DTAWLWPFKE TVRKCARSWS TAVTLMEQNT DFIFACSQAQ 300
QLEWVKSQYP GLHARLQEFA CRGQFVPVGG TWVEMDGNLP SGEAMVRQFL QGQNFFLQEF 360
GKMCSEFWLP DTFGYSAQLP QIMQGCGIKR FLTQKLSWNL VNSFPHHTFF WEGLDGSRVL 420
VHFPPGDSYG MQGSVEEVLK TVTNNRDKGR TNHSGFLFGF GDGGGGPTQT MLDRLKRLSN 480
TDGLPRVQLS SPGQLFTALE RDSGQLCTWV GELFLELHNG TYTTHAQLKK GNRECEQILH 540
DVEVLSSLAL ARSAQFLYPA AQLQHLWRLL LLNQFHDVVT GSCIQLVAED AMNYYEDIRS 600
HGNPLLSAAA AALCAGEPGP KGLLIINTLP WKRTEVLALP KPCGAHSLAL VTVPSIGYAP 660
APTPTSLQPL LPQQPVFVMQ ETDGSVTLDN GIIRVRLDPT GCLTSLVLVA SGREAIAEGA 720
LGNQFVLFDD VPLYWDAWDV MDYHLETRKP VLGQAGTLAV GTEGGLRGSA WFLLQISPNS 780
RLSQEVVLDV GCPYVRFHTE VHWHEAHKFL KVEFPARIRS PQATYEIQFG HLQRPTHNNT 840
SWDWARYEVW AHRWIDLSEC DFGLALLNNC KYGASVRGNV LSLSLLRAPK APDATADMGR 900
HEFTYALMPH KGSFQEAGVI HAAYNLNFPL LALPAPGPAP DTTWSAFSVS SPAVVLETIK 960
QAERCHQHRT LVLRLYEAHG SHVDCWLHTS LPVQEATLCD LLEQRDPTGH LSLQDNRLKL 1020
TFSPFQVRSL LLVLQSPPN 1039 
Gene Ontology
 GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006013; P:mannose metabolic process; IEA:InterPro. 
Interpro
 IPR011013; Gal_mutarotase_SF_dom.
 IPR011330; Glyco_hydro/deAcase_b/a-brl.
 IPR027291; Glyco_hydro_38/57_N.
 IPR011682; Glyco_hydro_38_C.
 IPR015341; Glyco_hydro_38_cen_dom.
 IPR000602; Glyco_hydro_38_N. 
Pfam
 PF09261; Alpha-mann_mid
 PF01074; Glyco_hydro_38
 PF07748; Glyco_hydro_38C 
SMART
 SM00872; Alpha-mann_mid 
PROSITE
  
PRINTS