UniProt Accession

 E5RHB5_HUMAN; E5RHB5 

Genbank Protein ID

 AC067817; AC108863 

Genbank Nucleotide ID

  

Protein Name

 Pleckstrin homology domain-containing family A member 2 

Protein Synonyms/Alias

  

Gene Name

 PLEKHA2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
113	EALNQASKITVPKGG	ubiquitination	[1]
118	ASKITVPKGGGLPMT	ubiquitination	[1, 2]
130	PMTTEVLKSLAAPPA	ubiquitination	[1, 2]
140	AAPPALEKKPQVAYK	ubiquitination	[1]
201	STGPPLIKSGYCVKQ	ubiquitination	[1]
207	IKSGYCVKQGNVRKS	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 249 AA 

Protein Sequence

Gene Ontology

 GO:0005543; F:phospholipid binding; IEA:InterPro. 

Interpro

 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 

Pfam

 PF00169; PH 

SMART

 SM00233; PH 

PROSITE

 PS50003; PH_DOMAIN 

PRINTS