UniProt Accession

 HSP13_HUMAN; P48723; B2R616; Q8NE40 

Genbank Protein ID

 U04735; AF130249; AK312396; AL163206; CH471079; BC036370 

Genbank Nucleotide ID

 AAA16954.1; AAD21091.1; BAG35313.1; CAB90390.1; EAX10056.1; AAH36370.1 

Protein Name

 Heat shock 70 kDa protein 13 

Protein Synonyms/Alias

 Microsomal stress-70 protein ATPase core; Stress-70 protein chaperone microsome-associated 60 kDa protein 

Gene Name

 HSPA13 

Gene Synonyms/Alias

 STCH 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
122	EIGRYPFKVLNKNGM	acetylation	[1]
122	EIGRYPFKVLNKNGM	ubiquitination	[2]
196	AANLAGLKILRVINE	ubiquitination	[2]
253	RAMSGNNKLGGQDFN	ubiquitination	[2]
368	FETEISRKLFDTLNE	ubiquitination	[2]
390	VPIQQVLKEGHLEKT	ubiquitination	[2]

Reference

 [1] Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.
 Morselli E, Mariño G, Bennetzen MV, Eisenberg T, Megalou E, Schroeder S, Cabrera S, Bénit P, Rustin P, Criollo A, Kepp O, Galluzzi L, Shen S, Malik SA, Maiuri MC, Horio Y, López-Otín C, Andersen JS, Tavernarakis N, Madeo F, Kroemer G.
 J Cell Biol. 2011 Feb 21;192(4):615-29. [PMID: 21339330]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Has peptide-independent ATPase activity. 

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Endoplasmic reticulum; Microsome; Nucleotide-binding; Reference proteome; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 471 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0043231; C:intracellular membrane-bounded organelle; TAS:ProtInc.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW. 

Interpro

 IPR018181; Heat_shock_70_CS.
 IPR013126; Hsp_70_fam. 

Pfam

 PF00012; HSP70 

SMART

  

PROSITE

 PS00297; HSP70_1
 PS00329; HSP70_2
 PS01036; HSP70_3 

PRINTS

 PR00301; HEATSHOCK70.