| Tag | Content |
|---|
| CPLM ID | CPLM-011889 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DER1-like family member protein 1 |
Protein Synonyms/Alias | |
Gene Name | DFM1 |
Gene Synonyms/Alias | YDR411C; D9461.2 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 231 | IWGMISRKADPTYGI | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | May be involved in the degradation process of some misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear and its inability to complement der1 mutations, suggests either that it is not involved in degradation process of misfolded proteins, or that it participates in the destruction of specific misfolded ER luminal proteins. |
Sequence Annotation | |
Keyword | Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Stress response; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 341 AA |
Protein Sequence | MAGPRNVRTL HGNGGRNNDV MGPKEFWLNI PPITRTLFTL AIVMTIVGRL NLINPWYFIY 60
VWNLTFKKVQ IWRLLTSCVM LSSRAMPALM ELYSIYDRSS QLERGHFGPG LSNRRGPMVT 120
VDYAYYLCFC ILAITTATTI IYGSYYPVVL TSGFISCITY TWSIDNANVQ IMFYGLIPVW 180
GKYFPLIQLF ISFVFNEGDF VISLIGFTTG YLYTCLDTHT LGPIWGMISR KADPTYGISP 240
NGKFSTPWWF TSLYARITGA HNETATFNNN FANVPSSQRE TRTFSGRGQR LGTAPATLSQ 300
TSGTDSGRAS GSQLRSGPSN LNQFQGRGQR VGQTNSPSDS Q 341 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IDA:SGD. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; ISM:SGD. GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD. GO:0030433; P:ER-associated protein catabolic process; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |