UniProt Accession

 MLRV_MOUSE; P51667; Q6P8P4; Q9QVP3 

Genbank Protein ID

 M91602; AK002367; AK146674; BC061144 

Genbank Nucleotide ID

 AAA39796.1; BAB22045.1; BAE27350.1; AAH61144.1 

Protein Name

 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform 

Protein Synonyms/Alias

 MLC-2; MLC-2v 

Gene Name

 Myl2 

Gene Synonyms/Alias

 Mylpc 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
8	MAPKKAKKRIEGGSS	ubiquitination	[1]
46	NRDGFIDKNDLRDTF	ubiquitination	[1]
62	ALGRVNVKNEEIDEM	ubiquitination	[1]
91	TMFGEKLKGADPEET	ubiquitination	[1]
111	KVFDPEGKGSLKADY	ubiquitination	[1]
115	PEGKGSLKADYVREM	ubiquitination	[1]
132	TQAERFSKEEIDQMF	ubiquitination	[1]
165	IITHGEEKD******	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

 DOMAIN 24 59 EF-hand 1.
 DOMAIN 94 129 EF-hand 2.
 DOMAIN 130 165 EF-hand 3.
 MOD_RES 2 2 N,N,N-trimethylalanine.  

Keyword

 Calcium; Complete proteome; Cytoplasm; Metal-binding; Methylation; Motor protein; Muscle protein; Myosin; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 166 AA 

Protein Sequence

Gene Ontology

 GO:0030016; C:myofibril; IDA:MGI.
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0030017; C:sarcomere; IEA:UniProtKB-SubCell.
 GO:0005509; F:calcium ion binding; ISO:MGI.
 GO:0060048; P:cardiac muscle contraction; IGI:MGI.
 GO:0055003; P:cardiac myofibril assembly; IMP:MGI.
 GO:0003007; P:heart morphogenesis; IGI:MGI.
 GO:0042694; P:muscle cell fate specification; IMP:MGI.
 GO:0048747; P:muscle fiber development; IGI:MGI.
 GO:0030308; P:negative regulation of cell growth; IEA:Compara.
 GO:0009791; P:post-embryonic development; IGI:MGI.
 GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Compara. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 

Pfam

 PF00036; efhand 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS