CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006294
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mannosyl phosphorylinositol ceramide synthase SUR1 
Protein Synonyms/Alias
  
Gene Name
 SUR1 
Gene Synonyms/Alias
 BCL21; CSG1; LPE15; YPL057C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
159AFPAFLRKTSPLGVSubiquitination[1]
327GLRLKLSKSTSDTASubiquitination[1]
347RQQKRLRKDSNTNIVubiquitination[1]
361VLLKSSRKSDVYDLEubiquitination[1]
369SDVYDLEKNDSSKYSubiquitination[1]
374LEKNDSSKYSLGNNSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Involved in the synthesis of mannosyl phosphorylinositol ceramide. Catalyzes the addition of mannosyl to phosphorylinositol ceramide. Suppressor of RVS161 mutation. 
Sequence Annotation
 MOD_RES 349 349 Phosphoserine.  
Keyword
 Complete proteome; Glycosyltransferase; Membrane; Phosphoprotein; Reference proteome; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 382 AA 
Protein Sequence
MRKELKYLIC FNILLLLSII YYTFDLLTLC IDDTVKDAIL EEDLNPDAPP KPQLIPKIIH 60
QTYKTEDIPE HWKEGRQKCL DLHPDYKYIL WTDEMAYEFI KEEYPWFLDT FENYKYPIER 120
ADAIRYFILS HYGGVYIDLD DGCERKLDPL LAFPAFLRKT SPLGVSNDVM GSVPRHPFFL 180
KALKSLKHYD KYWFIPYMTI MGSTGPLFLS VIWKQYKRWR IPKNGTVRIL QPAYYKMHSY 240
SFFSITKGSS WHLDDAKLMK ALENHILSCV VTGFIFGFFI LYGEFTFYCW LCSKNFSNLT 300
KNWKLNAIKV RFVTILNSLG LRLKLSKSTS DTASATLLAR QQKRLRKDSN TNIVLLKSSR 360
KSDVYDLEKN DSSKYSLGNN SS 382 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005622; C:intracellular; IC:SGD.
 GO:0000030; F:mannosyltransferase activity; IMP:SGD.
 GO:0006688; P:glycosphingolipid biosynthetic process; IMP:SGD.
 GO:0006675; P:mannosyl-inositol phosphorylceramide metabolic process; IMP:SGD. 
Interpro
 IPR007577; GlycoTrfase_DXD_sugar-bd_CS. 
Pfam
 PF04488; Gly_transf_sug 
SMART
  
PROSITE
  
PRINTS