CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020693
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock 70 kDa protein 12B 
Protein Synonyms/Alias
  
Gene Name
 Hspa12b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
146YFEKFKMKIHSATDLubiquitination[1]
181AHALRFFKEHALQELubiquitination[1]
198QSECMLEKGAVRWVLubiquitination[1]
375FGEDFIAKFKRQRPAacetylation[2]
375FGEDFIAKFKRQRPAubiquitination[1]
664QFGDTEIKVTAVDVSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 MOD_RES 42 42 Phosphothreonine.  
Keyword
 ATP-binding; Complete proteome; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 685 AA 
Protein Sequence
MLTVPEMGLQ GLYISSSPER SPVPSPPGSP RTQESCGIAP LTPSQSPKPE ARALQQASFS 60
VVVAIDFGTT SSGYAFSFAS DPEAIHMMRK WEGGDPGVAH QKTPTCLLLT PEGIFHSFGY 120
TARDYYHDLD PEEARDWLYF EKFKMKIHSA TDLTLKTQLE AVNGKKMLAL EVFAHALRFF 180
KEHALQELRE QSECMLEKGA VRWVLTVPAI WKQPAKQFMR EAAYLAGLVS REDAEKLLIA 240
LEPEAASVYC RKLRLHQLMD LSSRTAGRGR LGERRSIDSS FRHAREQLRR SRHSRTFLVE 300
AGVGELWAEM QEGDRYMVAD CGGGTVDLTV HQLEQPHGTL KELYKASGGP YGAVGVDLAF 360
EQLLCRIFGE DFIAKFKRQR PAAWVDLTIA FEARKRTAGP HRAGALNISL PFSFIDFYRK 420
QRGHNVETAL RRSSVNLVKW SSQGMLRMSC EAMNELFQPT VSGIIQHIEM LLAKPEVQGV 480
KLLFLVGGFA ESAVLQHAVQ EALGTRGLRV VVPHDVGLTI LKGAVLFGQA PGVVRVRRSP 540
LTYGVGVLNR FVPGHHPPEK LLVRDGRRWC TDVFERFVAA EQSVALGEEV RRSYCPARPG 600
QRRVLINLYC CAAEDARFIT DPGVRKCGAL SLELEPEGCP ENTGTSPSRR EIRAAMQFGD 660
TEIKVTAVDV STNRSVRAAI DFLSN 685 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW. 
Interpro
 IPR026685; HSPA12. 
Pfam
  
SMART
  
PROSITE
 PS00297; HSP70_1
 PS00329; HSP70_2
 PS01036; HSP70_3 
PRINTS