CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037193
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Intraflagellar transport protein 88 homolog 
Protein Synonyms/Alias
  
Gene Name
 IFT88 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
114VRAAGFTKAALRGSAubiquitination[1]
236YQVIVKNKMFSNAGIubiquitination[1]
254NMGNIYLKQRNYSKAubiquitination[1]
277DQVPSVNKQMRIKIMubiquitination[1]
351PLEIDEDKYISPSDDubiquitination[1]
369NLVTEAIKNDHLRQMubiquitination[1]
386ERKAMAEKYIMTSAKubiquitination[1]
430ANDLEINKAVTYLRQubiquitination[1]
438AVTYLRQKDYNQAVEubiquitination[1]
448NQAVEILKVLEKKDSubiquitination[1]
458EKKDSRVKSAAATNLubiquitination[1]
499NPAALTNKGNTVFANubiquitination[1, 2, 3]
511FANGDYEKAAEFYKEubiquitination[1, 2, 3]
517EKAAEFYKEALRNDSubiquitination[1, 2]
681RRSGNYQKALDTYKDubiquitination[1]
687QKALDTYKDTHRKFPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 795 AA 
Protein Sequence
MKFTNTKVQM MQNVHLAPET DEDDLYSGYN DYNPIYDIEE LENDAAFQQA VRTSHGRRPP 60
ITAKISSTAV TRPIATGYGS KTSLASSIGR PMTGAIQDGV TRPMTAVRAA GFTKAALRGS 120
AFDPLSQSRG PASPLEAKKK DSPEEKIKQL EKEVNELVEE SCIANSCGDL KLALEKAKDA 180
GRKERVLVRQ REQVTTPENI NLDLTYSVLF NLASQYSVNE MYAEALNTYQ VIVKNKMFSN 240
AGILKMNMGN IYLKQRNYSK AIKFYRMALD QVPSVNKQMR IKIMQNIGVT FIQAGQYSDA 300
INSYEHIMSM APNLKAGYNL TICYFAIGDR EKMKKAFQKL ITVPLEIDED KYISPSDDPH 360
TNLVTEAIKN DHLRQMERER KAMAEKYIMT SAKLIAPVIE TSFAAGYDWC VEVVKASQYV 420
ELANDLEINK AVTYLRQKDY NQAVEILKVL EKKDSRVKSA AATNLSALYY MGKDFAQASS 480
YADIAVNSDR YNPAALTNKG NTVFANGDYE KAAEFYKEAL RNDSSCTEAL YNIGLTYEKL 540
NRLDEALDCF LKLHAILRNS AEVLYQIANI YELMENPSQA IEWLMQVVSV IPTDPQVLSK 600
LGELYDREGD KSQAFQYYYE SYRYFPCNIE VIEWLGAYYI DTQFWEKAIQ YFERASLIQP 660
TQVKWQLMVA SCFRRSGNYQ KALDTYKDTH RKFPENVECS GSVRTGHMER DPLNLLPRKS 720
VLPGPEIAKC NYFSGEKYYL SAFLSSSLHR SWIKRCSRIC QKTEEVGKNE RNKGTAHKVR 780
QRWQWGLPWQ KRRKC 795 
Gene Ontology
  
Interpro
 IPR006597; Sel1-like.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR013105; TPR_2.
 IPR019734; TPR_repeat. 
Pfam
 PF07719; TPR_2
 PF13174; TPR_6 
SMART
 SM00671; SEL1
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS