CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015110
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc transporter 6 
Protein Synonyms/Alias
 ZnT-6; Solute carrier family 30 member 6 
Gene Name
 SLC30A6 
Gene Synonyms/Alias
 ZNT6 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
308HVIGQLDKLIREVSTubiquitination[1, 2]
419PVTSTPAKPSSPPPEubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Golgi apparatus; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 461 AA 
Protein Sequence
MGTIHLFRKP QRSFFGKLLR EFRLVAADRR SWKILLFGVI NLICTGFLLM WCSSTNSIAL 60
TAYTYLTIFD LFRDGVSPFW LGWSQTPDLK WSTHLGLPKC WDNRRELPCL SNSLMTCLIS 120
YWVTLRKPSP VYSFGFERLE VLAVFASTVL AQLGALFILK ESAERFLEQP EIHTGRLLVG 180
TFVALCFNLF TMLSIRNKPF AYVSEAASTS WLQEHVADLS RSLCGIIPGL SSIFLPRMNP 240
FVLIDLAGAF ALCITYMLIE INNYFAVDTA SAIAIALMTF GTMYPMSVYS GKVLLQTTPP 300
HVIGQLDKLI REVSTLDGVL EVRNEHFWTL GFGSLAGSVH VRIRRDANEQ MVLAHVTNRL 360
YTLVSTLTVQ IFKDDWIRPA LLSGPVAANV LNFSDHHVIP MPLLKGTDDL NPVTSTPAKP 420
SSPPPEFSFN TPGKNVNPVI LLNTQTRPYG FGLNHGHTPY SSMLNQGLGV PGIGATQGLR 480
TGFTNIPSRY GTNNRIGQPR P 501 
Gene Ontology
 GO:0000139; C:Golgi membrane; TAS:Reactome.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005385; F:zinc ion transmembrane transporter activity; IEA:Compara.
 GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
 GO:0006895; P:Golgi to endosome transport; IEA:Compara.
 GO:0055085; P:transmembrane transport; TAS:Reactome. 
Interpro
 IPR002524; Cation_efflux.
 IPR027469; Cation_efflux_TMD. 
Pfam
 PF01545; Cation_efflux 
SMART
  
PROSITE
  
PRINTS