CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015897
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Trafficking protein particle complex subunit 11 
Protein Synonyms/Alias
  
Gene Name
 TRAPPC11 
Gene Synonyms/Alias
 C4orf41 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
237IAFFSELKQDTQNALubiquitination[1]
245QDTQNALKNYRTAYNacetylation[2]
656LENLTQGKMCLVPGKubiquitination[1]
794VKLTAGLKPGQDANLubiquitination[1]
898AVKFVSTKFEHLERVubiquitination[1, 3, 4]
1033VRESLPVKYHLQNKTubiquitination[1]
1119IPTSIFVKPQGRLMDubiquitination[1, 3, 4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. 
Sequence Annotation
 MOD_RES 245 245 N6-acetyllysine.  
Keyword
 Acetylation; Alternative splicing; Complete proteome; ER-Golgi transport; Golgi apparatus; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1133 AA 
Protein Sequence
MSPTQWDFPV ELCCRPMAFV TLTGLDVVYN AVHRAVWDAF CANRRADRVP ISFKVLPGDH 60
EYPKCRPKRT SYEWYIPKGI LKTGWMNKHL NLVPALVVVF YELDWDEPQW KEKQSECATR 120
VEIVRQSLQG RNTKVAVVLI QKKTPLPPGE DVIASERAAA LCNACELSGK SLFVLPHTDH 180
LVGYIIRLEN AFYEHAQTYY YTEIRRVKSH KEFLNKTTHQ LLFVRHQFKI AFFSELKQDT 240
QNALKNYRTA YNLVHELRAH ETNILEIKTM AGFINYKICR LCFQHNTPLD AIAQFRKHID 300
LCKKKIGSAE LSFEHDAWMS KQFQAFGDLF DEAIKLGLTA IQTQNPGFYY QQAAYYAQER 360
KQLAKTLCNH EASVMYPNPD PLETQTGVLD FYGQRSWRQG ILSFDLSDPE KEKVGILAIQ 420
LKERNVVHSE IIITLLSNAV AQFKKYKCPR MKSHLMVQMG EEYYYAKDYT KALKLLDYVM 480
CDYRSEGWWT LLTSVLTTAL KCSYLMAQLK DYITYSLELL GRASTLKDDQ KSRIEKNLIN 540
VLMNESPDPE PDCDILAVKT AQKLWADRIS LAGSNIFTIG VQDFVPFVQC KAKFHAPSFH 600
VDVPVQFDIY LKADCPHPIR FSKLCVSFNN QEYNQFCVIE EASKANEVLE NLTQGKMCLV 660
PGKTRKLLFK FVAKTEDVGK KIEITSVDLA LGNETGRCVV LNWQGGGGDA ASSQEALQAA 720
RSFKRRPKLP DNEVHWDSII IQASTMIISR VPNISVHLLH EPPALTNEMY CLVVTVQSHE 780
KTQIRDVKLT AGLKPGQDAN LTQKTHVTLH GTELCDESYP ALLTDIPVGD LHPGEQLEKM 840
LYVRCGTVGS RMFLVYVSYL INTTVEEKEI VCKCHKDETV TIETVFPFDV AVKFVSTKFE 900
HLERVYADIP FLLMTDLLSA SPWALTIVSS ELQLAPSMTT VDQLESQVDN VILQTGESAS 960
ECFCLQCPSL GNIEGGVATG HYIISWKRTS AMENIPIITT VITLPHVIVE NIPLHVNADL 1020
PSFGRVRESL PVKYHLQNKT DLVQDVEISV EPSDAFMFSG LKQIRLRILP GTEQEMLYNF 1080
YPLMAGYQQL PSLNINLLRF PNFTNQLLRR FIPTSIFVKP QGRLMDDTSI AAA 1133 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 
Interpro
 IPR012880; DUF1683_C.
 IPR021773; Foie-gras_1. 
Pfam
 PF11817; Foie-gras_1
 PF07919; Gryzun 
SMART
  
PROSITE
  
PRINTS