CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004477
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA replication terminus site-binding protein 
Protein Synonyms/Alias
 Ter-binding protein 
Gene Name
 tus 
Gene Synonyms/Alias
 tau; b1610; JW1602 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
46FSLPEVKKEDEHNPLacetylation[1]
119SHIQHINKLKTTFEHacetylation[1]
192EVLAQLEKSLKSPRSacetylation[1]
227AALPQNAKLKIKRPVacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence. 
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; DNA replication; DNA-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 309 AA 
Protein Sequence
MARYDLVDRL NTTFRQMEQE LAIFAAHLEQ HKLLVARVFS LPEVKKEDEH NPLNRIEVKQ 60
HLGNDAQSLA LRHFRHLFIQ QQSENRSSKA AVRLPGVLCY QVDNLSQAAL VSHIQHINKL 120
KTTFEHIVTV ESELPTAARF EWVHRHLPGL ITLNAYRTLT VLHDPATLRF GWANKHIIKN 180
LHRDEVLAQL EKSLKSPRSV APWTREEWQR KLEREYQDIA ALPQNAKLKI KRPVKVQPIA 240
RVWYKGDQKQ VQHACPTPLI ALINRDNGAG VPDVGELLNY DADNVQHRYK PQAQPLRLII 300
PRLHLYVAD 309 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0043565; F:sequence-specific DNA binding; IDA:EcoCyc.
 GO:0071807; P:replication fork arrest involved in DNA replication termination; IDA:EcoCyc. 
Interpro
 IPR008865; DNA_replication_term_site-bd. 
Pfam
 PF05472; Ter 
SMART
  
PROSITE
  
PRINTS