UniProt Accession

 D39U1_HUMAN; Q9NRG7; Q6ZW71; Q9BVQ3 

Genbank Protein ID

 AF226050; AK123513; AL132800; BC000989 

Genbank Nucleotide ID

 AAF86950.1; AAH00989.1 

Protein Name

 Epimerase family protein SDR39U1 

Protein Synonyms/Alias

 Short-chain dehydrogenase/reductase family 39U member 1 

Gene Name

 SDR39U1 

Gene Synonyms/Alias

 C14orf124; HCDI 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
102	RWNETFQKEVIGSRL	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 Putative NADP-dependent oxidoreductase. 

Sequence Annotation

 NP_BIND 57 58 NADP.
 NP_BIND 84 88 NADP.
 BINDING 108 108 NADP.  

Keyword

 3D-structure; Alternative splicing; Complete proteome; NADP; Oxidoreductase; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 319 AA 

Protein Sequence

Gene Ontology

 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. 

Interpro

 IPR013549; DUF1731_C.
 IPR016040; NAD(P)-bd_dom.
 IPR010099; Sugar_nucleotide_Epase_put. 

Pfam

 PF08338; DUF1731 

SMART

  

PROSITE

  

PRINTS