CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044410
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptotagmin I, isoform CRA_b 
Protein Synonyms/Alias
 Synaptotagmin-1 
Gene Name
 SYT1 
Gene Synonyms/Alias
 hCG_2016754 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
330KKKTTIKKNTLNPYYubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 419 AA 
Protein Sequence
MVSESHHEAL AAPPVTTVAT VLPSNATEPA SPGEGKEDAF SKLKEKFMNE LHKIPLPPWA 60
LIAIAIVAVL LVLTCCFCIC KKCLFKKKNK KKGKEKGGKN AINMKDVKDL GKTMKDQDDD 120
AETGLTDGEE KEEPKEEEKL GKLQYSLDYD FQNNQLLVGI IQAAELPALD MGGTSDPYVK 180
VFLLPDKKKK FETKVHRKTL NPVFNEQFTF KVPYSELGGK TLVMAVYDFD RFSKHDIIGE 240
FKVPMNTVDF GHVTEEWRDL QSAEKEEQEK LGDICFSLRY VPTAGKLTVV ILEAKNLKKM 300
DVGGLSDPYV KIHLMQNGKR LKKKKTTIKK NTLNPYYNES FSFEVPFEQI QKVQVVVTVL 360
DYDKIGKNDA IGKVFVGYNS TGAELRHWSD MLANPRRPIA QWHTLQVEEE VDAMLAVKK 419 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0008021; C:synaptic vesicle; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR020477; C2_dom.
 IPR018029; C2_membr_targeting.
 IPR001565; Synaptotagmin.
 IPR015428; Synaptotagmin1. 
Pfam
 PF00168; C2 
SMART
 SM00239; C2 
PROSITE
 PS50004; C2 
PRINTS
 PR00360; C2DOMAIN.
 PR00399; SYNAPTOTAGMN.