| Tag | Content |
|---|
| CPLM ID | CPLM-005060 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cell cycle protein kinase DBF2 |
Protein Synonyms/Alias | |
Gene Name | DBF2 |
Gene Synonyms/Alias | YGR092W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 130 | ISRRQRTKQVLEYLQ | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Is probably a Ser/Thr-protein kinase that may function in initiation of DNA synthesis and also in late nuclear division. |
Sequence Annotation | DOMAIN 177 477 Protein kinase.
DOMAIN 478 555 AGC-kinase C-terminal.
NP_BIND 183 191 ATP (By similarity).
ACT_SITE 300 300 Proton acceptor (By similarity).
BINDING 206 206 ATP (By similarity).
MOD_RES 17 17 Phosphoserine.
MOD_RES 20 20 Phosphoserine.
MOD_RES 74 74 Phosphoserine.
MOD_RES 374 374 Phosphoserine. |
Keyword | ATP-binding; Cell cycle; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 572 AA |
Protein Sequence | MLSKSEKNVD LLAGNMSNLS FDGHGTPGGT GLFPNQNITK RRTRPAGIND SPSPVKPSFF 60
PYEDTSNMDI DEVSQPDMDV SNSPKKLPPK FYERATSNKT QRVVSVCKMY FLEHYCDMFD 120
YVISRRQRTK QVLEYLQQQS QLPNSDQIKL NEEWSSYLQR EHQVLRKRRL KPKNRDFEMI 180
TQVGQGGYGQ VYLARKKDTK EVCALKILNK KLLFKLNETK HVLTERDILT TTRSEWLVKL 240
LYAFQDLQSL YLAMEFVPGG DFRTLLINTR CLKSGHARFY ISEMFCAVNA LHDLGYTHRD 300
LKPENFLIDA KGHIKLTDFG LAAGTISNER IESMKIRLEK IKDLEFPAFT EKSIEDRRKM 360
YNQLREKEIN YANSMVGSPD YMALEVLEGK KYDFTVDYWS LGCMLFESLV GYTPFSGSST 420
NETYDNLRRW KQTLRRPRQS DGRAAFSDRT WDLITRLIAD PINRLRSFEH VKRMSYFADI 480
NFSTLRSMIP PFTPQLDSET DAGYFDDFTS EADMAKYADV FKRQDKLTAM VDDSAVSSKL 540
VGFTFRHRNG KQGSSGILFN GLEHSDPFST FY 572 |
Gene Ontology | GO:0005935; C:cellular bud neck; IDA:SGD. GO:0005816; C:spindle pole body; IDA:SGD. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:1901916; F:protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis; IMP:SGD. GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. GO:0000280; P:nuclear division; IMP:SGD. GO:0007035; P:vacuolar acidification; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |