CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005741
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Endochitinase 
Protein Synonyms/Alias
 Soluble cell wall protein 2 
Gene Name
 CTS1 
Gene Synonyms/Alias
 SCW2; YLR286C; L8003.13 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
504AAGKLNGKSTCTEGEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Chitinase is required for cell separation during growth of Saccharomyces cerevisiae. 
Sequence Annotation
 REGION 21 327 Catalytic.
 REGION 481 562 Chitin-binding, high affinity.
 ACT_SITE 157 157 Proton donor (By similarity).
 CARBOHYD 553 553 N-linked (GlcNAc...) (Potential).  
Keyword
 3D-structure; Carbohydrate metabolism; Cell wall; Cell wall biogenesis/degradation; Chitin degradation; Chitin-binding; Complete proteome; Direct protein sequencing; Glycoprotein; Glycosidase; Hydrolase; Polysaccharide degradation; Reference proteome; Secreted; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 562 AA 
Protein Sequence
MSLLYIILLF TQFLLLPTDA FDRSANTNIA VYWGQNSAGT QESLATYCES SDADIFLLSF 60
LNQFPTLGLN FANACSDTFS DGLLHCTQIA EDIETCQSLG KKVLLSLGGA SGSYLFSDDS 120
QAETFAQTLW DTFGEGTGAS ERPFDSAVVD GFDFDIENNN EVGYSALATK LRTLFAEGTK 180
QYYLSAAPQC PYPDASVGDL LENADIDFAF IQFYNNYCSV SGQFNWDTWL TYAQTVSPNK 240
NIKLFLGLPG SASAAGSGYI SDTSLLESTI ADIASSSSFG GIALWDASQA FSNELNGEPY 300
VEILKNLLTS ASQTATTTVA TSKTSAASTS SASTSSASTS QKKTTQSTTS TQSKSKVTLS 360
PTASSAIKTS ITQTTKTLTS STKTKSSLGT TTTESTLNSV AITSMKTTLS SQITSAALVT 420
PQTTTTSIVS SAPIQTAITS TLSPATKSSS VVSLQTATTS TLSPTTTSTS SGSTSSGSTS 480
SDSTARTLAK ELNAQYAAGK LNGKSTCTEG EIACSADGKF AVCDHSAWVY MECASGTTCY 540
AYDSGDSVYT QCNFSYLESN YF 562 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0005783; C:endoplasmic reticulum; IDA:SGD.
 GO:0005576; C:extracellular region; IDA:SGD.
 GO:0009277; C:fungal-type cell wall; IDA:SGD.
 GO:0005635; C:nuclear envelope; IDA:SGD.
 GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
 GO:0008843; F:endochitinase activity; IDA:SGD.
 GO:0006032; P:chitin catabolic process; IC:SGD.
 GO:0007109; P:cytokinesis, completion of separation; IMP:SGD.
 GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW. 
Interpro
 IPR005089; CBM_fam19.
 IPR001579; Glyco_hydro_18_chit_AS.
 IPR013781; Glyco_hydro_catalytic_dom.
 IPR017853; Glycoside_hydrolase_SF. 
Pfam
 PF03427; CBM_19 
SMART
  
PROSITE
 PS01095; CHITINASE_18 
PRINTS